EFHC1 and SLAIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EFHC1	SLAIN1
Description		EF-hand domain containing 1	SLAIN motif family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Neuronal Cell Body Mitotic Spindle Axonemal A Tubule Inner Sheath	Cytoplasm Cytoskeleton Microtubule Plus-end
	Molecular Function	Calcium Ion Binding Protein Binding Alpha-tubulin Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Flagellated Sperm Motility Regulation Of Cell Division Cilium-dependent Cell Motility	Microtubule Nucleation Positive Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization
Pathways
Drugs
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)	Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Craniofacial microsomia ( 26853712) Metabolite levels ( 23823483)
Interacting Genes		68 interacting genes: AKT1 CACNA1E CALCOCO2 CFAP161 CHCHD3 CIMIP1 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCNJ5-AS1 KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN YJU2B ZBED1	50 interacting genes: AIRIM AKAP9 ARHGEF5 ARMC7 ATOSB BCAS2 CARD9 COX5B CPSF7 CRACR2A DDX6 DMRTB1 EFHC1 EXOSC8 FBXO7 FHL2 FHL3 FRS3 GOLGA1 HNRNPF HOMER3 HOXC8 HSF2BP KCTD9 KIF9 KRT31 LMO3 MAPRE1 MAPRE3 NDEL1 NTAQ1 NXF1 PATZ1 PAX9 PDLIM7 PFDN5 PRC1 PRPF31 PSMA3 QKI RBM10 RBM14 RBPMS RFPL3 SAXO4 SIAH1 TBC1D22B TFAP2D TSSK3 ZNF76
Entrez ID		114327	122060
HPRD ID		10583	13400
Ensembl ID		ENSG00000096093	ENSG00000139737
Uniprot IDs		B2CKC5 Q5JVL4	A0A0A0MSS3 A0A994J5K0 B7Z326 Q5T6P1 Q7L0J2 Q8ND83
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Protein Binding	Protein Binding Microtubule Organizing Center MRNA Splicing, Via Spliceosome Mitotic Spindle Astral Microtubule End MRNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Binding Identical Protein Binding Cytoskeleton Organization RNA Splicing Microtubule-based Process Cytoplasmic Stress Granule Membraneless Organelle Assembly RNA Processing Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Microtubule Cytoskeleton Organization Sperm Flagellum Regulation Of MRNA Processing Cytoplasm Nucleus Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Podosome Assembly Microtubule Binding Protein Localization To Microtubule Regulation Of Microtubule Polymerization Regulation Of Microtubule-based Process
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