CERCAM and GEMIN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CERCAM	GEMIN4
Description		cerebral endothelial cell adhesion molecule	gem nuclear organelle associated protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Cajal Bodies
	Molecular Function	Protein Binding Identical Protein Binding Procollagen Galactosyltransferase Activity	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Cell Adhesion Leukocyte Cell-cell Adhesion	Spliceosomal SnRNP Assembly RRNA Processing MRNA Processing RNA Splicing
Pathways			snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Body mass index ( 26426971) Systemic lupus erythematosus ( 26606652)	Prostate cancer ( 23535732)
Interacting Genes		38 interacting genes: ABHD5 ATG9A CDC23 CREB5 CYSRT1 DSCR9 FANCL FKBP7 FNDC11 GEMIN4 GLRX3 GOPC HOXA1 KLHL38 KRTAP15-1 KRTAP26-1 KRTAP3-3 KRTAP6-2 KRTAP8-1 KRTAP9-3 LASP1 LCOR MAGED1 MKRN3 OTX1 P4HA3 POGZ POU4F2 RBM11 RHOXF2 RUNX1 SFT2D1 SOHLH1 TENT5B UBL5 VENTX VGLL3 ZDHHC15	57 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNASE2 RNF10 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35
Entrez ID		51148	50628
HPRD ID		16705	07370
Ensembl ID		ENSG00000167123	ENSG00000179409
Uniprot IDs		Q5T4B2	I3L2C7 P57678 Q8WUM5 Q9HC39
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Chromatin	SMN-Sm Protein Complex Protein-RNA Complex Assembly Spliceosomal SnRNP Assembly U2 SnRNP 7-methylguanosine Cap Hypermethylation RNA Processing U4 SnRNP Methylosome Intermediate Filament Small Nuclear Ribonucleoprotein Complex RNA Splicing U1 SnRNP Tertiary Granule U5 SnRNP Presynaptic Dense Core Vesicle Exocytosis U2-type Prespliceosome Assembly U12-type Spliceosomal Complex MRNA Processing Perichromatin Fibrils U2-type Spliceosomal Complex RNA Polymerase II Complex Binding U2-type Catalytic Step 2 Spliceosome RNA Metabolic Process Positive Regulation Of Dendritic Cell Differentiation PICln-Sm Protein Complex Neuronal Dense Core Vesicle Exocytosis U1 SnRNP Binding Neutrophil Degranulation Transcription Elongation-coupled Chromatin Remodeling Keratin Filament RISC-loading Complex Dense Core Granule Exocytosis U4/U6 X U5 Tri-snRNP Complex RNA Binding Anaphase-promoting Complex Binding Calcium Ion-regulated Exocytosis Of Neurotransmitter RISC Complex Assembly MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly SiRNA Binding SMN Complex U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions Cytosol Locomotor Rhythm Ubiquitin Ligase Activator Activity Gemini Of Cajal Bodies Protein Binding Ribonucleoside Triphosphate Phosphatase Activity MRNA Metabolic Process
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