DYNC1LI1 and NUP85

Number of citations of the paper that reports this interaction (PMID 10893222)
41

Data Source:
HPRD (in vivo)

		DYNC1LI1	NUP85
Gene Name		dynein, cytoplasmic 1, light intermediate chain 1	nucleoporin 85kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytoplasm Centrosome Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane	Kinetochore Condensed Chromosome Kinetochore Nuclear Envelope Spindle Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane
	Molecular Function	Microtubule Motor Activity ATP Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Transport Microtubule-based Movement Mitotic Nuclear Division Metabolic Process Viral Process Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Lamellipodium Assembly Small Molecule Metabolic Process Macrophage Chemotaxis MRNA Transport Transmembrane Transport
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown Mitotic Anaphase SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Resolution of Sister Chromatid Cohesion Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: IKBKG NUP85 RAB4A REL	5 interactors: DYNC1LI1 EEF1G PIK3R1 PRKACA VIM
Entrez ID		51143	79902
HPRD ID		10917	01363
Ensembl ID		ENSG00000144635	ENSG00000125450
Uniprot IDs		E9PHI6 Q9Y6G9	B4DYG7 Q9BW27
PDB IDs
Enriched GO Terms of Interacting Partners?		NIK/NF-kappaB Signaling I-kappaB Kinase/NF-kappaB Signaling Immune System Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Neuron Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Neuron Death Positive Regulation Of Cytokine Production Intracellular Signal Transduction Inflammatory Response Positive Regulation Of Interleukin-12 Biosynthetic Process Signal Transduction Macrophage Chemotaxis Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Cytokine Production Viral Process Signaling Cell Communication Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway RNA Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Response To Cytokine Positive Regulation Of NIK/NF-kappaB Signaling B Cell Homeostasis Mitotic Nuclear Envelope Disassembly Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Regulation Of NIK/NF-kappaB Signaling Innate Immune Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Nuclear Envelope Disassembly Membrane Organization Positive Regulation Of Interleukin-12 Production Lamellipodium Assembly Lamellipodium Organization RNA Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Cell Death Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Rab Protein Signal Transduction Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway Gene Expression Regulation Of Interleukin-12 Production Lymphocyte Homeostasis	Regulation Of Glucose Import Movement Of Cell Or Subcellular Component Cellular Glucose Homeostasis Viral Process Cellular Response To Light Stimulus Regulation Of Glucose Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Dense Core Granule Biogenesis NFAT Protein Import Into Nucleus Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Mitotic Cell Cycle Cellular Response To Radiation Histone H3-T6 Phosphorylation Transcription Factor Import Into Nucleus Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Myeloid Cell Differentiation Intrinsic Apoptotic Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Apoptotic Process Response To Fibroblast Growth Factor Platelet Activation Programmed Cell Death Glucose Homeostasis Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Leukocyte Migration Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Intracellular Transport Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Intracellular Protein Transport Peptidyl-serine Autophosphorylation Positive Regulation Of Spindle Checkpoint Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Cell Cycle Bergmann Glial Cell Differentiation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Cell Migration Desmosome Assembly
Tagcloud ?		a431 accumulate centrally colocalises compartment disrupts dlic dynein endosomal endosomes erc fip3 gtpase henceforth links minus onto pericentrosomal pericentrosomally periphery precedes rab11 rab11a recruits recycling sorting symbol ternary truncation
Tagcloud (Difference) ?		a431 accumulate centrally colocalises compartment disrupts dlic dynein endosomal endosomes erc fip3 gtpase henceforth links minus onto pericentrosomal pericentrosomally periphery precedes rab11 rab11a recruits recycling sorting symbol ternary truncation
Tagcloud (Intersection) ?