NUP85

Description		nucleoporin 85
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Actin Cytoskeleton Membrane Nuclear Pore Outer Ring Nuclear Membrane Ciliary Basal Body
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	MRNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Chemotaxis Protein Transport Lamellipodium Assembly Positive Regulation Of DNA-templated Transcription Macrophage Chemotaxis MRNA Transport Nephron Development
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Systemic sclerosis ( 31672989)
Interacting Genes		6 interacting genes: DYNC1LI1 EEF1G GET4 PIK3R1 PRKACA VIM
Entrez ID		79902
HPRD ID		01363
Ensembl ID		ENSG00000125450
Uniprot IDs		F5H0W7 J3KT10 Q9BW27
PDB IDs		5A9Q 7PEQ 7R5J 7R5K
Enriched GO Terms of Interacting Partners?
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