IER3IP1 and TMPPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IER3IP1	TMPPE
Description		immediate early response 3 interacting protein 1	transmembrane protein with metallophosphoesterase domain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle	Membrane
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Type B Pancreatic Cell Differentiation Positive Regulation Of Extracellular Matrix Constituent Secretion Chromatin Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Brain Development Negative Regulation Of Cell Population Proliferation Gene Expression Protein Transport Organ Growth Glucose Homeostasis Negative Regulation Of Apoptotic Process Cell Maturation Positive Regulation Of Protein Secretion Insulin Metabolic Process Regulation Of Fibroblast Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Fruit consumption ( 32066663)	Asthma ( 31619474 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27	35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1
Entrez ID		51124	643853
HPRD ID		13727	18951
Ensembl ID		ENSG00000134049	ENSG00000188167
Uniprot IDs		Q9Y5U9	Q6ZT21
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipid Biosynthetic Process Sphingosine N-acyltransferase Activity Membrane Lipid Metabolic Process Lipid Metabolic Process Response To Endoplasmic Reticulum Stress	Membrane Plasma Membrane Organelle Membrane Fusion SNAP Receptor Activity Vesicle Fusion SNARE Complex Organelle Fusion Membrane Fusion Vesicle Docking Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering External Side Of Plasma Membrane Membrane Docking
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