IER3IP1 and TMEM167A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IER3IP1	TMEM167A
Description		immediate early response 3 interacting protein 1	transmembrane protein 167A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Type B Pancreatic Cell Differentiation Positive Regulation Of Extracellular Matrix Constituent Secretion Chromatin Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Brain Development Negative Regulation Of Cell Population Proliferation Gene Expression Protein Transport Organ Growth Glucose Homeostasis Negative Regulation Of Apoptotic Process Cell Maturation Positive Regulation Of Protein Secretion Insulin Metabolic Process Regulation Of Fibroblast Apoptotic Process	Protein Secretion Constitutive Secretory Pathway Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Fruit consumption ( 32066663)	Chin dimples ( 27182965) Clozapine-induced agranulocytosis ( 25187353) Osteoarthritis biomarkers ( 25057126) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 25760438)
Interacting Genes		43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27	2 interacting genes: IER3IP1 TRIM14
Entrez ID		51124	153339
HPRD ID		13727	14490
Ensembl ID		ENSG00000134049	ENSG00000174695
Uniprot IDs		Q9Y5U9	Q8TBQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipid Biosynthetic Process Sphingosine N-acyltransferase Activity Membrane Lipid Metabolic Process Lipid Metabolic Process Response To Endoplasmic Reticulum Stress	Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Regulation Of Fibroblast Apoptotic Process Type B Pancreatic Cell Differentiation Regulation Of Extracellular Matrix Constituent Secretion Insulin Metabolic Process Positive Regulation Of Extracellular Matrix Constituent Secretion Enteroendocrine Cell Differentiation Protein K48-linked Deubiquitination Positive Regulation Of Extracellular Matrix Organization
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