COQ4 and COQ9

Number of citations of the paper that reports this interaction (PubMedID 27499296)
55

Data Source:
BioGRID (pull down, affinity chromatography technology)

		COQ4	COQ9
Description		coenzyme Q4	coenzyme Q9
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex Ubiquinone Biosynthesis Complex	Mitochondrion Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex
	Molecular Function	Protein Binding Lyase Activity 4-hydroxy-3-methoxy-5-polyprenylbenzoate Decarboxylase Activity	Protein Binding Enzyme Activator Activity Lipid Binding Isoprenoid Binding Protein Homodimerization Activity
	Biological Process	Ubiquinone Biosynthetic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process
Pathways		Ubiquinol biosynthesis	Ubiquinol biosynthesis
Drugs
Diseases			Coenzyme Q10 deficiency
GWAS		Body mass index ( 26426971) Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: COQ7 COQ9 MAGEA2 MAGEA2B	33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2
Entrez ID		51117	57017
HPRD ID		16741	13157
Ensembl ID		ENSG00000167113	ENSG00000088682
Uniprot IDs		Q9Y3A0	O75208
PDB IDs			4RHP 6AWL 6DEW 7SSP 7SSS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Acetylation Ubiquinone Biosynthesis Complex Negative Regulation Of Protein Sumoylation Positive Regulation Of Ubiquitin-protein Transferase Activity Ubiquinone Biosynthetic Process Ubiquinone Metabolic Process Quinone Metabolic Process Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity Ketone Biosynthetic Process Cellular Senescence Ketone Metabolic Process Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination PML Body 3-demethoxyubiquinol 3-hydroxylase Activity 3-demethoxyubiquinone 3-hydroxylase (NADH) Activity Isoprenoid Binding Positive Regulation Of Post-translational Protein Modification Histone Deacetylase Binding DNA-binding Transcription Factor Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Extrinsic Component Of Mitochondrial Inner Membrane Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding Positive Regulation Of Catalytic Activity Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Modification Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Mitochondrial Inner Membrane Small Molecule Biosynthetic Process Regulation Of Catalytic Activity Negative Regulation Of Protein Metabolic Process Protein Catabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Modification Process Determination Of Adult Lifespan Negative Regulation Of Biosynthetic Process Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Metabolic Process Monooxygenase Activity Aerobic Electron Transport Chain
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