RPS27L and HFM1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		RPS27L	HFM1
Description		ribosomal protein S27 like	helicase for meiosis 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Ribosome Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex	Nucleus
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Translation Activator Activity Metal Ion Binding	Nucleotide Binding Nucleic Acid Binding DNA Helicase Activity Helicase Activity ATP Binding Zinc Ion Binding Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Ribosomal Small Subunit Assembly Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Signaling Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Translation	Resolution Of Meiotic Recombination Intermediates Reciprocal Meiotic Recombination Meiotic Cell Cycle
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944)	Metabolite levels ( 23823483) Response to fenofibrate (HDL cholesterol levels) ( 27002377)
Interacting Genes		3 interacting genes: CLIP4 HFM1 ZRSR2	2 interacting genes: FAM107A RPS27L
Entrez ID		51065	164045
HPRD ID		18003	18568
Ensembl ID		ENSG00000185088	ENSG00000162669
Uniprot IDs		Q71UM5	A2PYH4 B4DYS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Pre-mRNA 3'-splice Site Binding U2AF Complex U12-type Spliceosomal Complex Nucleic Acid Binding Microtubule Plus-end Binding Microtubule Plus-end Reciprocal Meiotic Recombination Resolution Of Meiotic Recombination Intermediates DNA Helicase Activity Homologous Recombination Spliceosomal Complex Assembly	Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Negative Regulation Of Long-term Synaptic Potentiation Translation Activator Activity Ribosomal Small Subunit Assembly Regulation Of Cell Cycle Process Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Positive Regulation Of Protein Metabolic Process Negative Regulation Of Focal Adhesion Assembly Actin Filament Polymerization Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell-matrix Adhesion Cytosolic Small Ribosomal Subunit Regulation Of Long-term Synaptic Potentiation Protein-containing Complex Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Actin Polymerization Or Depolymerization Regulation Of Focal Adhesion Assembly Actin Filament Bundle Organization Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Protein-containing Complex Organization Actin Filament Bundle Assembly Negative Regulation Of Cell-substrate Adhesion Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell-substrate Junction Organization Protein Polymerization Mitotic DNA Integrity Checkpoint Signaling Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Response To Steroid Hormone Stimulus Stress Fiber Ruffle Membrane DNA Damage Checkpoint Signaling Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Post-translational Protein Modification
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?