HFM1

Description		helicase for meiosis 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Helicase Activity Helicase Activity ATP Binding Zinc Ion Binding Hydrolase Activity Isomerase Activity ATP Hydrolysis Activity Metal Ion Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Reciprocal Meiotic Recombination Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Response to fenofibrate (HDL cholesterol levels) ( 27002377)
Interacting Genes		2 interacting genes: FAM107A RPS27L
Entrez ID		164045
HPRD ID		18568
Ensembl ID		ENSG00000162669
Uniprot IDs		A2PYH4 B4DYS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Negative Regulation Of Long-term Synaptic Potentiation Translation Activator Activity Ribosomal Small Subunit Assembly Regulation Of Cell Cycle Process Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Positive Regulation Of Protein Metabolic Process Negative Regulation Of Focal Adhesion Assembly Actin Filament Polymerization Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell-matrix Adhesion Cytosolic Small Ribosomal Subunit Regulation Of Long-term Synaptic Potentiation Protein-containing Complex Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Actin Polymerization Or Depolymerization Regulation Of Focal Adhesion Assembly Actin Filament Bundle Organization Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Protein-containing Complex Organization Actin Filament Bundle Assembly Negative Regulation Of Cell-substrate Adhesion Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell-substrate Junction Organization Protein Polymerization Mitotic DNA Integrity Checkpoint Signaling Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Response To Steroid Hormone Stimulus Stress Fiber Ruffle Membrane DNA Damage Checkpoint Signaling Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Ubiquitination Positive Regulation Of Post-translational Protein Modification
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