GPR3 and ZNF593

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GPR3	ZNF593
Description		G protein-coupled receptor 3	zinc finger protein 593
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Sphingosine-1-phosphate Receptor Activity	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Ribonucleoprotein Complex Binding Metal Ion Binding Preribosome Binding
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Meiotic Nuclear Division Positive Regulation Of Cold-induced Thermogenesis	Ribosome Biogenesis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: GNPAT RXYLT1 ZNF593	10 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 POLR1H RAB1A SRPK2
Entrez ID		2827	51042
HPRD ID		02587	15866
Ensembl ID		ENSG00000181773	ENSG00000142684
Uniprot IDs		F1DAM5 P46089	O00488
PDB IDs		8U8F 8WW2 8X2K	1ZR9 6LSS 6LU8 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR3 8RL2
Enriched GO Terms of Interacting Partners?		Glycerone-phosphate O-acyltransferase Activity Ribitol Beta-1,4-xylosyltransferase Activity Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Transcription Regulatory Region DNA Binding Cerebellum Morphogenesis Paranodal Junction Assembly Preribosome Binding Ether Lipid Biosynthetic Process Protein O-linked Glycosylation Via Mannose Negative Regulation Of DNA Binding Regulation Of Transcription Regulatory Region DNA Binding Ether Lipid Metabolic Process O-acyltransferase Activity Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Ribonucleoprotein Complex Binding Regulation Of DNA Binding Peroxisomal Matrix	JNK Cascade Phosphorylation Protein Phosphorylation P38MAPK Cascade Stress-activated MAPK Cascade MAP Kinase Kinase Kinase Activity Stress-activated Protein Kinase Signaling Cascade Magnesium Ion Binding Regulation Of Stress-activated Protein Kinase Signaling Cascade Protein Kinase Activator Activity MAPK Cascade Positive Regulation Of Mitotic DNA Damage Checkpoint Mannosyltransferase Complex Defense Response Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Protein Serine Kinase Activity Alpha-1,6-mannosyltransferase Activity Intracellular Signaling Cassette Protein Serine/threonine Kinase Activity Negative Regulation Of Signaling I-kappaB Phosphorylation Linear Polyubiquitin Binding Negative Regulation Of Cell Communication Termination Of RNA Polymerase I Transcription Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress GPI Mannosyltransferase Activity
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