SSMEM1 and PLPP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSMEM1	PLPP1
Description		serine rich single-pass membrane protein 1	phospholipid phosphatase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Caveola Membrane Apical Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process		Lipid Metabolic Process Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Lipid Metabolic Process Sphingolipid Catabolic Process Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Androgen Receptor Signaling Pathway Phospholipid Dephosphorylation
Pathways			Sphingolipid catabolism
Drugs
Diseases
GWAS		Neurological blood protein biomarker levels ( 31320639)	Cocaine dependence ( 31212010) Heel bone mineral density ( 28869591 30598549)
Interacting Genes		99 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ARLN ATP6V0C BET1 BLCAP C11orf24 C1QL4 C5 CCL4L2 CDIPT CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 JAGN1 LAT LEPROTL1 LHFPL5 LNPEP MARCHF2 MCRS1 MFSD12 MFSD6 MIP MMD2 MS4A13 NINJ2 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35E3 SLC35H1 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC61A1 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1	5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1
Entrez ID		136263	8611
HPRD ID		14060	06178
Ensembl ID		ENSG00000165120	ENSG00000067113
Uniprot IDs		A0A3B3ISA2 Q8WWF3	O14494
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Water Channel Activity Phosphatidate Phosphatase Activity Transmembrane Transport Glycerol Transmembrane Transport Carbohydrate Transport Water Transport Polyol Transmembrane Transport Phospholipid Metabolic Process Alkenylglycerophosphocholine Hydrolase Activity Fluid Transport Phospholipid Dephosphorylation Plasma Membrane Channel Activity Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Diacylglycerol Diphosphate Phosphatase Activity Magnesium Ion Transmembrane Transport Magnesium Ion Transmembrane Transporter Activity Magnesium Ion Transport Carbohydrate Transmembrane Transport Amide Transport Glycerol Channel Activity Lipid Phosphatase Activity Renal Water Absorption One-carbon Compound Transport Urea Transmembrane Transporter Activity Farnesyl Diphosphate Metabolic Process Gap Junction-mediated Intercellular Transport Sphingosine-1-phosphate Phosphatase Activity CCR6 Chemokine Receptor Binding Antigen Processing And Presentation Of Peptide Antigen Response To Bacterium Chemotaxis Lysophosphatidic Acid Phosphatase Activity Inorganic Cation Transmembrane Transporter Activity Renal Water Transport Neutrophil Differentiation Glutamine Transport L-glutamine Transmembrane Transporter Activity Locomotion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Ammonium Channel Activity Urea Transmembrane Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Negative Regulation Of Protein Glutathionylation Positive Regulation Of Deacetylase Activity Fumarylpyruvate Hydrolase Activity Oxaloacetate Tautomerase Activity Acylpyruvate Hydrolase Activity Acetylpyruvate Hydrolase Activity Positive Regulation Of Monoatomic Ion Transport Oxaloacetate Decarboxylase Activity Release From Viral Latency Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity Regulation Of Cardiac Muscle Cell Membrane Potential CCR1 Chemokine Receptor Binding Oxaloacetate Metabolic Process CAMP Response Element Binding Protein Binding Sodium:potassium-exchanging ATPase Complex Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?