REG3A and ANXA3

Number of citations of the paper that reports this interaction (PubMedID 10662590)
0

Data Source:
HPRD (two hybrid, in vitro)

		REG3A	ANXA3
Description		regenerating family member 3 alpha	annexin A3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleus Cytoplasm Plasma Membrane Vesicle Membrane Membrane Phagocytic Vesicle Membrane Specific Granule Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding Carbohydrate Binding Signaling Receptor Activity Identical Protein Binding Peptidoglycan Binding Oligosaccharide Binding	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Acute-phase Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Response To Symbiotic Bacterium Response To Wounding Positive Regulation Of Keratinocyte Proliferation Response To Peptide Hormone Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing Inflammatory Response To Wounding Negative Regulation Of Inflammatory Response To Wounding Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Detection Of Glucose	Phagocytosis Positive Regulation Of Endothelial Cell Migration Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways		Antimicrobial peptides	Developmental Lineage of Pancreatic Ductal Cells
Drugs			Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases
GWAS		Body mass index ( 25673413) HDL cholesterol levels in HIV infection ( 33109212)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Daytime nap ( 33568662) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 22446963 30423114)
Interacting Genes		6 interacting genes: ANXA3 FN1 MDFI REG1A SDC2 TRHDE	6 interacting genes: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		5068	306
HPRD ID		01342	00111
Ensembl ID		ENSG00000172016	ENSG00000138772
Uniprot IDs		Q06141 Q53S56	P12429
PDB IDs		1UV0 2GO0 4MTH	1AII 1AXN
Enriched GO Terms of Interacting Partners?			Response To Symbiotic Bacterium Response To Symbiont Positive Regulation Of Detection Of Glucose Protein-folding Chaperone Binding Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Proteolysis Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Protein Refolding Negative Regulation Of Protein Folding RRNA (pseudouridine) Methyltransferase Activity Nucleologenesis Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Negative Regulation Of Cellular Component Organization B Cell Lineage Commitment Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Pentose-phosphate Shunt Junctional Membrane Complex Nucleolus Organization Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of Caveolin-mediated Endocytosis L-leucine Binding
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