REG3A and REG1A

Number of citations of the paper that reports this interaction (PubMedID 10662590)
0

Data Source:
HPRD (two hybrid, in vitro)

		REG3A	REG1A
Description		regenerating family member 3 alpha	regenerating family member 1 alpha
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Hormone Activity Protein Binding Carbohydrate Binding Signaling Receptor Activity Identical Protein Binding Peptidoglycan Binding Oligosaccharide Binding	Protein Binding Growth Factor Activity Carbohydrate Binding Signaling Receptor Activity Peptidoglycan Binding Oligosaccharide Binding Molecular Function Inhibitor Activity
	Biological Process	Acute-phase Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Response To Symbiotic Bacterium Response To Wounding Positive Regulation Of Keratinocyte Proliferation Response To Peptide Hormone Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing Inflammatory Response To Wounding Negative Regulation Of Inflammatory Response To Wounding Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Detection Of Glucose	Signal Transduction Positive Regulation Of Cell Population Proliferation Response To Peptide Hormone Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Antimicrobial peptides	Developmental Lineage of Pancreatic Acinar Cells
Drugs			N-acetyl-alpha-neuraminic acid Dexfosfoserine
Diseases
GWAS		Body mass index ( 25673413) HDL cholesterol levels in HIV infection ( 33109212)	Blood protein levels ( 30072576) Body mass index ( 26426971) Contrast sensitivity ( 24152035) Idiopathic downbeat nystagmus ( 32157568) Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ANXA3 FN1 MDFI REG1A SDC2 TRHDE	2 interacting genes: APP REG3A
Entrez ID		5068	5967
HPRD ID		01342	01338
Ensembl ID		ENSG00000172016	ENSG00000115386
Uniprot IDs		Q06141 Q53S56	A8K7G6 P05451
PDB IDs		1UV0 2GO0 4MTH	1LIT 1QDD
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Regulation Of Response To Calcium Ion Positive Regulation Of Gene Expression Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Antimicrobial Humoral Response Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Detection Of Glucose Positive Regulation Of Hydrogen Sulfide Biosynthetic Process Cellular Response To Wortmannin Response To Wortmannin Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Humoral Immune Response Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Cell Population Proliferation Positive Regulation Of Amyloid Fibril Formation Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Multicellular Organismal Process Growth Factor Receptor Binding Main Axon Positive Regulation Of Signal Transduction Response To Symbiotic Bacterium Response To Symbiont Response To Peptide Hormone Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity
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