REG3A and TRHDE

Number of citations of the paper that reports this interaction (PMID 10662590)
4

Data Source:
HPRD (in vitro, two hybrid)

		REG3A	TRHDE
Gene Name		regenerating islet-derived 3 alpha	thyrotropin-releasing hormone degrading enzyme
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Carbohydrate Binding	Aminopeptidase Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Acute-phase Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organismal Development Cell Proliferation Positive Regulation Of Keratinocyte Proliferation Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Wound Healing	Proteolysis Signal Transduction Cell-cell Signaling
Pathways
Drugs
Diseases
GWAS			Chemerin levels ( 20237162) Rheumatoid arthritis ( 21452313)
Protein-Protein Interactions		6 interactors: ANXA3 FN1 MDFI REG1A SDC2 TRHDE	1 interactors: REG3A
Entrez ID		5068	29953
HPRD ID		01342	09506
Ensembl ID		ENSG00000172016	ENSG00000072657
Uniprot IDs		Q06141 Q53S56	Q9UKU6
PDB IDs		1UV0 2GO0
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Keratinocyte Proliferation Negative Regulation Of Epidermal Cell Differentiation Regulation Of Keratinocyte Proliferation Regulation Of Keratinocyte Differentiation Negative Regulation Of Epithelial Cell Differentiation Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Acute-phase Response Regulation Of Epidermal Cell Differentiation Positive Regulation Of Wound Healing Regulation Of Epidermis Development Acute Inflammatory Response Regulation Of Wound Healing Regulation Of Epithelial Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Regulation Of Epithelial Cell Proliferation Inflammatory Response
Tagcloud ?		aberrantly aberrations aza believed carcinogenesis cpg demethylating deoxycytidine fifth island islet knock maybe messages methylated modulated negatively obvious pac pancreatic plasmid progress promotion regenerating remarkably restoration socs3 synergy worked	adenovirus balb became brother c57bl chr cxb degrading discriminating graves histocompatibility hyperthyroid hyperthyroidism immunization inbred intriguing linkage maps matings mhc overtly preimmunization progeny releasing sister t4 tbi thyrotoxic tsh
Tagcloud (Difference) ?		aberrantly aberrations aza believed carcinogenesis cpg demethylating deoxycytidine fifth island islet knock maybe messages methylated modulated negatively obvious pac pancreatic plasmid progress promotion regenerating remarkably restoration socs3 synergy worked	adenovirus balb became brother c57bl chr cxb degrading discriminating graves histocompatibility hyperthyroid hyperthyroidism immunization inbred intriguing linkage maps matings mhc overtly preimmunization progeny releasing sister t4 tbi thyrotoxic tsh
Tagcloud (Intersection) ?