TRHDE

Description		thyrotropin releasing hormone degrading enzyme
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Aminopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Pyroglutamyl-peptidase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Proteolysis Signal Transduction Cell-cell Signaling Peptide Catabolic Process
Pathways
Drugs
Diseases
GWAS		Chemerin levels ( 20237162) Diastolic blood pressure ( 26969751) General risk tolerance (MTAG) ( 30643258) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407) Rheumatoid arthritis ( 21452313) Tea consumption ( 31046077)
Interacting Genes		1 interacting genes: REG3A
Entrez ID		29953
HPRD ID		09506
Ensembl ID		ENSG00000072657
Uniprot IDs		Q9UKU6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Detection Of Glucose Response To Symbiotic Bacterium Response To Symbiont Inflammatory Response To Wounding Regulation Of Inflammatory Response To Wounding Negative Regulation Of Inflammatory Response To Wounding Oligosaccharide Binding Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Epidermal Cell Differentiation Peptidoglycan Binding Positive Regulation Of Keratinocyte Proliferation Positive Regulation Of Cytokine Production Involved In Inflammatory Response Acute-phase Response Regulation Of Keratinocyte Differentiation Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Keratinocyte Proliferation Negative Regulation Of Epithelial Cell Differentiation Positive Regulation Of Wound Healing Regulation Of Epidermal Cell Differentiation Regulation Of Epidermis Development Acute Inflammatory Response Regulation Of Cytokine Production Involved In Inflammatory Response Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Hormone Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Regulation Of Wound Healing Antimicrobial Humoral Response Regulation Of Epithelial Cell Differentiation Carbohydrate Binding Regulation Of Response To Wounding Negative Regulation Of Inflammatory Response Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Wounding Humoral Immune Response Signaling Receptor Activity Negative Regulation Of Defense Response Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Peptide Hormone
Tagcloud ?