CYHR1 and LGALS3

Number of citations of the paper that reports this interaction (PMID 10745073)
5

Data Source:
HPRD (two hybrid, in vitro)

		CYHR1	LGALS3
Gene Name		cysteine/histidine-rich 1	lectin, galactoside-binding, soluble, 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Perinuclear Region Of Cytoplasm	Immunological Synapse Proteinaceous Extracellular Matrix Extracellular Space Nucleus Spliceosomal Complex Cytoplasm Mitochondrial Inner Membrane Plasma Membrane External Side Of Plasma Membrane Membrane Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding	Protein Binding IgE Binding Carbohydrate Binding Chemoattractant Activity Laminin Binding Poly(A) RNA Binding
	Biological Process		Skeletal System Development Monocyte Chemotaxis MRNA Processing RNA Splicing Extracellular Matrix Organization Neutrophil Chemotaxis Epithelial Cell Differentiation Regulation Of T Cell Proliferation Innate Immune Response Negative Regulation Of Endocytosis Eosinophil Chemotaxis Macrophage Chemotaxis Negative Regulation Of T Cell Receptor Signaling Pathway Positive Chemotaxis Regulation Of T Cell Apoptotic Process Mononuclear Cell Migration Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Import Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Immunological Synapse Formation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Advanced glycosylation endproduct receptor signaling Innate Immune System
Drugs
Diseases
GWAS			Protein biomarker ( 23056639)
Protein-Protein Interactions		4 interactors: ALDH3A1 KPNA4 LGALS3 MAPK9	20 interactors: APP BARD1 C1GALT1C1 CSNK1A1 CSNK2A1 CSNK2A2 CUBN CYHR1 ELN FCGR2A GEMIN4 GOLGA2 LGALS3BP LIM2 MMP2 MYOC PPIG PRR13 SS18L1 SUFU
Entrez ID		50626	3958
HPRD ID		13107	01090
Ensembl ID		ENSG00000187954	ENSG00000131981
Uniprot IDs		Q6ZMK1	P17931
PDB IDs			1A3K 1KJL 1KJR 2NMN 2NMO 2NN8 2XG3 3AYA 3AYC 3AYD 3AYE 3T1L 3T1M 3ZSJ 3ZSK 3ZSL 3ZSM 4JC1 4JCK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Immunological Synapse Formation Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Positive Regulation Of Ion Transport Response To Stress Positive Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration JUN Phosphorylation Positive Regulation Of Prostaglandin Biosynthetic Process Establishment Of Protein Localization To Organelle Eosinophil Chemotaxis Eosinophil Migration Response To External Stimulus Protein Targeting Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Response To Inorganic Substance Positive Regulation Of Calcium Ion Import Monocyte Chemotaxis Response To Drug Protein Localization To Organelle Macrophage Chemotaxis Positive Regulation Of Icosanoid Secretion NLS-bearing Protein Import Into Nucleus Negative Regulation Of T Cell Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Regulation Of Calcium Ion Import Regulation Of Ion Transport Positive Regulation Of Fatty Acid Transport Response To Organic Substance Positive Chemotaxis Cytoplasmic Transport Response To Cytokine Positive Regulation Of Macrophage Derived Foam Cell Differentiation Release Of Cytochrome C From Mitochondria Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Transport Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Organonitrogen Compound Positive Regulation Of Chemokine Production Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Lipid Regulation Of T Cell Apoptotic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Immune Response Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Endocytosis	Neuron Differentiation Neuron Projection Development Negative Regulation Of Cellular Protein Catabolic Process Wnt Signaling Pathway Neuron Development Negative Regulation Of Protein Catabolic Process Endocytosis Generation Of Neurons Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Neurogenesis Cell Projection Organization Cell Morphogenesis Involved In Differentiation Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Protein Processing Neuron Maturation Cell Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Axonogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nervous System Development Negative Regulation Of Proteasomal Protein Catabolic Process Neuron Projection Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Proteolysis Synaptic Growth At Neuromuscular Junction ERBB2 Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Anatomical Structure Morphogenesis Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Chromosome Organization Collateral Sprouting In Absence Of Injury Mitotic Cell Cycle Extracellular Matrix Disassembly
Tagcloud ?			clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Difference) ?			clnd23 clnd8 colorectal cytoscape database david degs detailed differentially downloaded downregulated enriched foxo3 go gse8671 microarray network omnibus ontology pgfdr ppi shed spia string tcf7l2 tfats top upregulated valuable
Tagcloud (Intersection) ?