CD207 and ZCCHC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD207	ZCCHC12
Description		CD207 molecule	zinc finger CCHC-type containing 12
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Endocytic Vesicle Clathrin-coated Endocytic Vesicle Membrane Early Endosome Membrane	Nucleus
	Molecular Function	Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Immune Response Defense Response To Virus
Pathways		Cross-presentation of soluble exogenous antigens (endosomes) Cross-presentation of soluble exogenous antigens (endosomes)
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Atopic dermatitis ( 26482879) Erythema nodosum in inflammatory bowel disease ( 24487271) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Schizophrenia x sex interaction ( 34099189) Serum metabolite levels ( 33031748)
Interacting Genes		6 interacting genes: CREB3 ERGIC3 GRAMD2B SCD SEC22A ZCCHC12	27 interacting genes: ABHD5 APP APPBP2 ATP6V0C CD207 FADD FATE1 KPNA3 LMO1 MAGEA11 MCRS1 MX1 PNMA1 PRMT1 RNF40 RUSF1 SPOP STX2 SUMO1 SUMO2 SUMO3 TADA2A TFCP2 TMEM43 TMEM79 TNF UBE2I
Entrez ID		50489	170261
HPRD ID		07278	06616
Ensembl ID		ENSG00000116031	ENSG00000174460
Uniprot IDs		Q9UJ71	Q6PEW1
PDB IDs		3C22 3KQG 3P5D 3P5E 3P5F 3P5G 3P5H 3P5I 3P7F 3P7G 3P7H 4AK8 4N32 4N33 4N34 4N35 4N36 4N37 4N38 5G6U 7WZ8 7YTQ
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Monounsaturated Fatty Acid Biosynthetic Process Positive Regulation Of Deacetylase Activity Palmitoyl-CoA 9-desaturase Activity Endoplasmic Reticulum Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Transporter Complex, Golgi To ER Stearoyl-CoA 9-desaturase Activity Transporter Complex Release From Viral Latency Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water CCR1 Chemokine Receptor Binding	Protein Sumoylation Protein Tag Activity Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin-like Protein Ligase Binding Presynaptic Cytosol Postsynaptic Cytosol Positive Regulation Of Proteolysis Regulation Of Proteolysis PML Body Small Protein Activating Enzyme Binding Protein Modification By Small Protein Conjugation Necroptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Identical Protein Binding Post-translational Protein Modification Nucleoplasm Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Protein Catabolic Process Nuclear Pore Astrocyte Activation Negative Regulation Of DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Amyloid-beta Clearance SUMO Transferase Activity Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Storage Negative Regulation Of Blood Circulation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification Process Positive Regulation Of Myeloid Cell Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of MiRNA Transcription Regulation Of Type II Interferon Production Regulation Of RNA Metabolic Process Microglial Cell Activation Defense Response To Virus Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Catabolic Process Regulation Of JNK Cascade
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