ORM2 and BBS5

		ORM2	BBS5
Description		orosomucoid 2	Bardet-Biedl syndrome 5
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome Blood Microparticle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Membrane Centriolar Satellite BBSome Ciliary Basal Body Cell Projection Ciliary Membrane
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production	Heart Looping Visual Perception Protein Transport Cell Projection Organization Melanosome Transport Motile Cilium Assembly Intracellular Transport Cilium Assembly
Pathways		Platelet degranulation Neutrophil degranulation	BBSome-mediated cargo-targeting to cilium
Drugs		Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Bardet-Biedl syndrome (BBS)
GWAS			Iris heterochromicity ( 30895295)
Interacting Genes		3 interacting genes: CYP39A1 PRDX6 STK3	4 interacting genes: CRADD KLC3 TOM1 TOM1L2
Entrez ID		5005	129880
HPRD ID		00725	10353
Ensembl ID		ENSG00000228278	ENSG00000163093
Uniprot IDs		P19652	A0A0S2Z626 Q8N3I7
PDB IDs		3APU 3APV 3APW 3APX 7OUB	6XTB
Enriched GO Terms of Interacting Partners?		Steroid 7-alpha-hydroxylase Activity Oxysterol 7-alpha-hydroxylase Activity 24S-hydroxycholesterol 7-alpha-hydroxylase Activity Primitive Hemopoiesis Neural Tube Formation Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Endocardium Development 1-acylglycerophosphocholine O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Peroxiredoxin Activity Lipid Catabolic Process Cholesterol Catabolic Process BBSome
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