BBS5 and KLC3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BBS5	KLC3
Gene Name		Bardet-Biedl syndrome 5	kinesin light chain 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol BBSome Ciliary Basal Body Ciliary Membrane	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding Phosphatidylinositol-3-phosphate Binding	Microtubule Motor Activity Microtubule Binding Kinesin Binding
	Biological Process	Heart Looping Organelle Organization Visual Perception Protein Transport Melanosome Transport Cilium Assembly Motile Cilium Assembly Response To Stimulus	Axon Cargo Transport Metabolic Process
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium	MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CRADD KLC3	35 interactors: ABI3 BBS5 CCDC36 CCDC64B CCNH CENPP CEP57L1 CROCC DTX2 GEM IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 PDE4DIP QARS SNAP47 SPERT STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		129880	147700
HPRD ID		10353	03212
Ensembl ID		ENSG00000163093	ENSG00000104892
Uniprot IDs		Q8N3I7	Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?		Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Axon Cargo Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Mitotic G1 DNA Damage Checkpoint Cellular Response To Mechanical Stimulus G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction In Response To DNA Damage Activation Of Cysteine-type Endopeptidase Activity Mitotic DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Extrinsic Apoptotic Signaling Pathway Zymogen Activation Signal Transduction By P53 Class Mediator Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Microtubule-based Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Endopeptidase Activity Regulation Of Cell Cycle G1/S Phase Transition Cytoskeleton-dependent Intracellular Transport Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Peptidase Activity DNA Damage Checkpoint Mitotic Cell Cycle Checkpoint Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Response To Mechanical Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Protein Processing	Protein Localization Organelle Organization Cellular Localization Organelle Localization Establishment Of Localization In Cell Establishment Of Organelle Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Vesicle Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Synaptic Vesicle Fusion To Presynaptic Membrane Establishment Of Vesicle Localization Cellular Protein Localization Cell Cycle Chromosome Organization Positive Regulation Of Intracellular Transport Regulation Of Mitochondrion Organization Protein Transport Microtubule-based Process Establishment Of Protein Localization Intracellular Transport Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Synaptic Transmission Negative Regulation Of Protein Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Hormone Metabolic Process Developmental Process Anatomical Structure Development Substantia Nigra Development Regulation Of Synaptic Plasticity Nervous System Development Regulation Of Establishment Of Protein Localization Embryonic Digestive Tract Development Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Glutaminyl-tRNA Aminoacylation Regulation Of Primitive Erythrocyte Differentiation Histone H2B Conserved C-terminal Lysine Ubiquitination Glucocorticoid Catabolic Process Microtubule Anchoring Cell Cycle Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Intracellular Transport Vesicle Fusion Mitotic Cell Cycle Neural Nucleus Development Synaptic Vesicle Exocytosis Pituitary Gland Development
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