ATP4B and ZC4H2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP4B	ZC4H2
Description		ATPase H+/K+ transporting subunit beta	zinc finger C4H2-type containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Potassium:proton Exchanging ATPase Complex Sodium:potassium-exchanging ATPase Complex Membrane Apical Plasma Membrane	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex Neuronal Cell Body Synapse Postsynaptic Membrane
	Molecular Function	ATPase Activator Activity Protein Binding P-type Potassium:proton Transporter Activity Heterocyclic Compound Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Cell Adhesion Intracellular Potassium Ion Homeostasis Response To Lipopolysaccharide Sodium Ion Export Across Plasma Membrane PH Reduction Potassium Ion Transmembrane Transport Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Noradrenergic Neuron Development Protein Monoubiquitination Nervous System Development Neuromuscular Junction Development Spinal Cord Motor Neuron Differentiation Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Transcription Regulatory Region DNA Binding
Pathways		Ion transport by P-type ATPases
Drugs		Dexlansoprazole Vonoprazan
Diseases
GWAS		Height ( 31562340)	Male-pattern baldness ( 28196072)
Interacting Genes		6 interacting genes: AGO3 BPGM CCNDBP1 GPR42 STX1A ZC4H2	22 interacting genes: ATP4B CMIP DGCR6 FAM161B GCC1 GEM HOXB5 KXD1 MECOM PLEKHN1 PRPH RNF151 SORBS3 TRIM14 ZNF223 ZNF250 ZNF408 ZNF490 ZNF524 ZNF669 ZNF688 ZNF76
Entrez ID		496	55906
HPRD ID		00669	06584
Ensembl ID		ENSG00000186009	ENSG00000126970
Uniprot IDs		P51164	Q9NQZ6
PDB IDs
Enriched GO Terms of Interacting Partners?			Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleus
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