SPANXN2 and NOL12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPANXN2	NOL12
Description		SPANX family member N2	nucleolar protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding	Single-stranded DNA Binding RNA Binding Protein Binding RRNA Binding Identical Protein Binding
	Biological Process
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Basophil count ( 32888494) Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30224653)
Interacting Genes		50 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BIVM CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A GPRASP3 H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84	19 interacting genes: APP BEND7 CDCA7L CDK4 CEP70 DVL2 DVL3 KIAA1191 KRTAP10-6 KRTAP10-7 MCC SAP18 SF3B3 SLC25A38 SOD2 SPANXN2 SSX2IP TERF1 TSPYL2
Entrez ID		494119	79159
HPRD ID		18091	17537
Ensembl ID		ENSG00000268988	ENSG00000273899
Uniprot IDs		Q5MJ10	Q9UGY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus DNA Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly SMN-Sm Protein Complex Nucleoplasm Protein-RNA Complex Assembly Zinc Ion Binding Sequence-specific DNA Binding SMN Complex Gemini Of Cajal Bodies Protein Binding	Frizzled Binding Positive Regulation Of Neuron Projection Arborization Response To Manganese Ion Regulation Of Neuron Projection Arborization Positive Regulation Of JNK Cascade Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of JNK Cascade Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nitric Oxide Metabolic Process Response To Xenobiotic Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Acetylcholine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Glycine Import Into Mitochondrion
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