SPANXN2 and RPL27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPANXN2	RPL27
Description		SPANX family member N2	ribosomal protein L27
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse Extracellular Exosome Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process		Cytoplasmic Translation RRNA Processing Translation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS
Interacting Genes		50 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BIVM CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A GPRASP3 H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84	6 interacting genes: CHUK EP300 FOXP1 NRP1 PTEN SPANXN2
Entrez ID		494119	6155
HPRD ID		18091	09602
Ensembl ID		ENSG00000268988	ENSG00000131469
Uniprot IDs		Q5MJ10	P61353
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 8A3D 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Nucleus DNA Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly SMN-Sm Protein Complex Nucleoplasm Protein-RNA Complex Assembly Zinc Ion Binding Sequence-specific DNA Binding SMN Complex Gemini Of Cajal Bodies Protein Binding	Negative Regulation Of Developmental Growth Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Development Regulation Of Androgen Receptor Signaling Pathway Heart Development Nuclear Androgen Receptor Binding Negative Regulation Of Growth Negative Regulation Of Organ Growth Postsynapse Organization Regulation Of Intracellular Signal Transduction Regulation Of Developmental Growth Positive Regulation Of Intracellular Signal Transduction Response To Acetate Cell Differentiation Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Canonical NF-kappaB Signal Transduction Myeloid Cell Development Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Regulation Of Neuron Projection Development Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Axonogenesis Regulation Of Cell-substrate Junction Organization Regulation Of Focal Adhesion Assembly Otic Placode Development Basal Dendrite Development Response To Amino Acid Cytoplasmic Side Of Plasma Membrane Cellular Developmental Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of DNA-binding Transcription Factor Activity Anatomical Structure Morphogenesis Response To Cholecystokinin Beta-catenin Binding Regulation Of Phosphorus Metabolic Process Histone H2B Acetyltransferase Activity Animal Organ Development Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Nervous System Development
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