SPANXN2 and FAM193B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPANXN2	FAM193B
Description		SPANX family member N2	family with sequence similarity 193 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		50 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BIVM CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A GPRASP3 H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84	12 interacting genes: ATXN1 CDC25A CNOT11 GOLGA2 GSK3A GSK3B LDOC1 MAPK8 PKN2 SPANXN2 TRIM23 TRIM27
Entrez ID		494119	54540
HPRD ID		18091	07671
Ensembl ID		ENSG00000268988	ENSG00000146067
Uniprot IDs		Q5MJ10	Q96PV7
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus DNA Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly SMN-Sm Protein Complex Nucleoplasm Protein-RNA Complex Assembly Zinc Ion Binding Sequence-specific DNA Binding SMN Complex Gemini Of Cajal Bodies Protein Binding	Regulation Of Autophagy Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Protein Binding Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Autophagy Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Cellular Response To Interleukin-3 Excitatory Postsynaptic Potential Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Catabolic Process Beta-catenin Destruction Complex Regulation Of Postsynaptic Membrane Potential Protein Kinase A Catalytic Subunit Binding Protein Serine Kinase Activity Tau-protein Kinase Activity Negative Regulation Of Catabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Viral Protein Processing Positive Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Protein Binding Regulation Of Glycogen Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Membrane Permeability Regulation Of Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Kinase Activity Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Glycogen Metabolic Process Protein Modification Process Tau Protein Binding Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity Postsynapse Transferase Activity Positive Regulation Of Metabolic Process Negative Regulation Of UDP-glucose Catabolic Process Kinase Activity Regulation Of Mitochondrial Membrane Permeability Regulation Of Microtubule Anchoring At Centrosome JUN Phosphorylation Regulation Of Protein Modification Process Glycogen Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Membrane Permeability Positive Regulation Of Neuron Apoptotic Process
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