NUP88 and CD82

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		NUP88	CD82
Description		nucleoporin 88	CD82 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol	Plasma Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Protein Binding
	Biological Process	Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus MRNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Adult body size ( 32376654) Lymphocyte count ( 32888494) Mean platelet volume ( 32888494)	Blond vs. brown/black hair color ( 30531825) Cadmium levels ( 26025379) Hemostatic factors and hematological phenotypes ( 22443383) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Lymphocyte count ( 32888494) Male-pattern baldness ( 27182965) Mean reticulocyte volume ( 32888494) Plasma parathyroid hormone levels ( 30134803) Red cell distribution width ( 27863252 28957414 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) TNF-alpha gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683)
Interacting Genes		5 interacting genes: AGTR1 CD82 NUP214 NUP98 TFIP11	29 interacting genes: BDKRB2 BRCC3 CANX CD19 CD4 CD63 CHRM5 CREB3 EGFR ERBB2 ERBB3 FFAR2 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 KLRC1 LRP1 NLRP3 NUP88 PTGFRN SMIM3 VANGL1
Entrez ID		4927	3732
HPRD ID		03974	09004
Ensembl ID		ENSG00000108559	ENSG00000085117
Uniprot IDs		B4DP20 J3KMX1 Q99567	P27701
PDB IDs		7MNI 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Angiotensin Type I Receptor Activity Symbiont Entry Into Host Cell Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Convergent Extension Involved In Neural Plate Elongation Trans-synaptic Signaling By Trans-synaptic Complex, Modulating Synaptic Transmission RNA Export From Nucleus Nuclear Export Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Telomere Tethering At Nuclear Periphery Import Into Nucleus MRNA Transport Protein Import Into Nucleus Nuclear Pore Cytoplasmic Side Of Nuclear Pore Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Biological Process Involved In Interaction With Host Convergent Extension Involved In Organogenesis RNA Transport Nuclear Pore Cytoplasmic Filaments Convergent Extension Involved In Gastrulation Trans-synaptic Signaling By Trans-synaptic Complex Axon Choice Point Recognition Protein Localization To Nucleus Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Protection From Non-homologous End Joining At Telomere Regulation Of Renal Sodium Excretion Positive Regulation Of Neuron Projection Arborization Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Telomere Localization Nuclear Envelope Nucleobase-containing Compound Transport Nuclear Pore Outer Ring Nuclear Pore Complex Assembly Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Trans-synaptic Signaling, Modulating Synaptic Transmission Nuclear Transport Nucleocytoplasmic Transport Nuclear Inclusion Body Nuclear Export Signal Receptor Activity Convergent Extension Nuclear Pore Nuclear Basket Nuclear Pore Organization	Cell Surface Receptor Complex Integrin Complex Cell Surface Receptor Signaling Pathway Membrane Positive Regulation Of Cell Adhesion Regulation Of Multicellular Organismal Process Signaling Receptor Activity Cell-matrix Adhesion Regulation Of Cell Adhesion ERBB2 Signaling Pathway Immune System Process MHC Class II Protein Complex Binding Regulation Of Leukocyte Cell-cell Adhesion Cell-substrate Adhesion ERBB2-EGFR Signaling Pathway Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Immune System Process Integrin-mediated Signaling Pathway Signal Transduction Positive Regulation Of Immune Response Positive Regulation Of Cell-cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Plasma Membrane Peptide Antigen Assembly With MHC Class II Protein Complex Regulation Of Cell Migration ERBB3:ERBB2 Complex MHC Class II Protein Complex Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Coreceptor Activity Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Motility Regulation Of Immune System Process Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Immune Effector Process Focal Adhesion Clathrin-coated Endocytic Vesicle Membrane Regulation Of Locomotion Regulation Of Intracellular Signal Transduction Regulation Of Cell Activation Integrin Alpha4-beta1 Complex ERBB Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Localization To Cell Periphery
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