NINJ2 and RNASEK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NINJ2	RNASEK
Description		ninjurin 2	ribonuclease K
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex
	Molecular Function	Protein Binding Cholesterol Binding Membrane Destabilizing Activity	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Nervous System Development Cytolysis Tissue Regeneration	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte count ( 27863252 32888494) Mean platelet volume ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Rheumatic heart disease ( 34106200) Stroke ( 19369658) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 32888494)
Interacting Genes		79 interacting genes: AMIGO1 AQP6 ARL13B BCL2L13 BTNL9 CD69 CD79A CEACAM3 CHODL CLEC17A CLEC7A CPLX4 CREB3L1 CYBC1 EBP ELOVL4 ELOVL5 EREG ERGIC3 ERVFRD-1 EVI2B FAM209A FAM210B FCGRT FCRL4 FNDC9 GJA1 GJA8 GPR152 GPR42 GPX8 ICAM3 IFNGR1 IL3RA JAGN1 KCNJ6 KIR2DL3 KIR3DL3 LDLRAD1 LHFPL5 LMNA LYPD5 LYVE1 M6PR MGST3 MMGT1 MR1 MUC1 ODF4 PIGP PVR REEP4 RIC3 RNASEK SCN3B SLAMF8 SLC10A1 SLC10A6 SLC35H1 SLC66A1 SLC7A14 SLC7A8 SSMEM1 STX1A STX2 TM4SF20 TMEM101 TMEM139 TMEM14B TMEM31 TMEM51 TMEM52B TMEM86B TMEM9 TMPRSS2 TMX2 TSPAN12 VMA21 VSIG1	26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21
Entrez ID		4815	440400
HPRD ID		09530	17568
Ensembl ID		ENSG00000171840	ENSG00000219200
Uniprot IDs		A0A590UJR9 B4DJC1 F5H3L1 F8WBZ3 Q9NZG7	A0A0C4DH89 Q6P5S7
PDB IDs		8SZB	6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Intracellular PH Reduction External Side Of Plasma Membrane Bile Acid:sodium Symporter Activity Lysosomal Lumen Acidification	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy
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