ATP1A4 and CTAG1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP1A4	CTAG1A
Description		ATPase Na+/K+ transporting subunit alpha 4	cancer/testis antigen 1A
Image
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Cell Projection Membrane Raft Sperm Midpiece Photoreceptor Cell Cilium Rod Photoreceptor Outer Segment	Cytoplasm
	Molecular Function	Nucleotide Binding P-type Sodium:potassium-exchanging Transporter Activity Protein Binding ATP Binding P-type Potassium Transmembrane Transporter Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Kinase Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Cell Surface Receptor Signaling Pathway Spermatogenesis Fertilization Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Intracellular Monoatomic Cation Homeostasis Intracellular Potassium Ion Homeostasis Flagellated Sperm Motility Regulation Of Cellular PH Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Regulation Of Membrane Potential Establishment Of Localization In Cell Potassium Ion Transmembrane Transport Transport Across Blood-brain Barrier Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs		Bisacodyl Tegoprazan
Diseases
GWAS		Composite immunoglobulin trait (IgA/IgG) ( 28628107) Gout ( 22179738)
Interacting Genes		3 interacting genes: CTAG1A CTAG1B RIC8A	76 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1B CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		480	246100
HPRD ID		09541	06607
Ensembl ID		ENSG00000132681	ENSG00000268651
Uniprot IDs		Q13733	P78358
PDB IDs		8ZYJ	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		TRNA Threonylcarbamoyladenosine Metabolic Process Cell-cell Adhesion Involved In Gastrulation TRNA Metabolic Process Cell Migration Involved In Gastrulation	Protein Binding Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Skeletal Muscle Atrophy Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Regulation Of Protein Ubiquitination Cytoplasm Skeletal Muscle Adaptation Striated Muscle Atrophy Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
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