ATP1A4

Description		ATPase Na+/K+ transporting subunit alpha 4
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GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Cell Projection Membrane Raft Sperm Midpiece Photoreceptor Cell Cilium Rod Photoreceptor Outer Segment
	Molecular Function	Nucleotide Binding P-type Sodium:potassium-exchanging Transporter Activity Protein Binding ATP Binding P-type Potassium Transmembrane Transporter Activity ATP Hydrolysis Activity ATPase-coupled Monoatomic Cation Transmembrane Transporter Activity Kinase Binding Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Cell Surface Receptor Signaling Pathway Spermatogenesis Fertilization Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Intracellular Monoatomic Cation Homeostasis Intracellular Potassium Ion Homeostasis Flagellated Sperm Motility Regulation Of Cellular PH Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Regulation Of Membrane Potential Establishment Of Localization In Cell Potassium Ion Transmembrane Transport Transport Across Blood-brain Barrier Proton Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs		Bisacodyl Tegoprazan
Diseases
GWAS		Composite immunoglobulin trait (IgA/IgG) ( 28628107) Gout ( 22179738)
Interacting Genes		3 interacting genes: CTAG1A CTAG1B RIC8A
Entrez ID		480
HPRD ID		09541
Ensembl ID		ENSG00000132681
Uniprot IDs		Q13733
PDB IDs		8ZYJ
Enriched GO Terms of Interacting Partners?		TRNA Threonylcarbamoyladenosine Metabolic Process Cell-cell Adhesion Involved In Gastrulation TRNA Metabolic Process Cell Migration Involved In Gastrulation
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