STRA6 and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STRA6	KRTAP10-6
Description		signaling receptor and transporter of retinol STRA6	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Protein-containing Complex	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Retinal Binding Retinol Binding Retinol Transmembrane Transporter Activity Signaling Receptor Activity	Protein Binding
	Biological Process	Blood Vessel Development Kidney Development Pulmonary Valve Morphogenesis Ventricular Septum Development Heart Development Learning Feeding Behavior Lung Development Adrenal Gland Development Female Genitalia Development Retinol Transport Vocal Learning Camera-type Eye Development Ear Development Nose Morphogenesis Lung Alveolus Development Positive Regulation Of Behavior Digestive Tract Morphogenesis Embryonic Digestive Tract Development Developmental Growth Smooth Muscle Tissue Development Artery Morphogenesis Cognition Neuromuscular Process Head Development Head Morphogenesis Face Morphogenesis Lung Vasculature Development Diaphragm Development Embryonic Camera-type Eye Formation Eyelid Development In Camera-type Eye Uterus Morphogenesis Alveolar Primary Septum Development Pulmonary Artery Morphogenesis Paramesonephric Duct Development Vitamin A Import Into Cell Ductus Arteriosus Closure
Pathways		The canonical retinoid cycle in rods (twilight vision) Defective visual phototransduction due to STRA6 loss of function	Keratinization
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Inhibitory control ( 29251981) Optic disc size ( 31809533)
Interacting Genes		4 interacting genes: GLRX3 KRTAP10-6 KRTAP6-3 NDUFB7	87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		64220	386674
HPRD ID		18122	11192
Ensembl ID		ENSG00000137868	ENSG00000188155
Uniprot IDs		B3KPB8 Q9BX79	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?			Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process
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