NAP1L1 and PHB

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		NAP1L1	PHB
Gene Name		nucleosome assembly protein 1-like 1	prohibitin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Membrane Melanosome	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding
	Biological Process	DNA Replication Nucleosome Assembly Positive Regulation Of Cell Proliferation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Cell Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Histone Deacetylation Negative Regulation Of Cell Growth Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Progesterone Receptor Signaling Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Interleukin-6 DNA Biosynthetic Process Negative Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Diastolic blood pressure ( 19430483) Prostate cancer ( 23535732)
Protein-Protein Interactions		14 interactors: CREBBP CSNK2B DLST EP300 FSD1 HBA1 MED10 NR2F6 PHB POT1 SP1 TERF1 TP53 TPX2	19 interactors: ANXA2 COX6C E2F1 ESR1 HDAC1 LONRF3 MAP3K10 NAP1L1 NCOR1 RAF1 RB1 RBL1 RBL2 SIN3A SMARCA2 SMARCA4 SUMO4 TP53 XPO1
Entrez ID		4673	5245
HPRD ID		01248	01454
Ensembl ID		ENSG00000187109	ENSG00000167085
Uniprot IDs		B3KV44 B7Z4K9 B7Z9C2 F8W543 P55209	A8K401 B4DY47 P35232 Q53FV0
PDB IDs			1LU7
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomerase Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation By Host Of Viral Transcription Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase N-terminal Protein Amino Acid Acetylation Negative Regulation Of DNA Metabolic Process Rhythmic Process Cellular Response To Hypoxia Positive Regulation Of Metabolic Process Cellular Response To Decreased Oxygen Levels Mitotic Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomerase Activity Cellular Response To Oxygen Levels Chromatin Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of DNA Replication Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomere Maintenance Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Androgen Receptor Signaling Pathway Notch Signaling Pathway Cellular Nitrogen Compound Metabolic Process RNA-dependent DNA Replication Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Cellular Metabolic Process Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Photoperiodism Entrainment Of Circadian Clock N-terminal Protein Amino Acid Modification Organelle Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Gene Expression	Chromatin Organization Negative Regulation Of Gene Expression Chromosome Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Chromatin Remodeling Transcription, DNA-templated Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Transcription, DNA-templated Response To Transforming Growth Factor Beta RNA Biosynthetic Process Regulation Of Fibroblast Proliferation Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Aortic Smooth Muscle Cell Differentiation Regulation Of Cell Proliferation Regulation Of Cell Cycle Phase Transition Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Positive Regulation Of Gene Expression Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cell Cycle Process Gene Expression Negative Regulation Of Signaling Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Phosphorylation Rhythmic Process
Tagcloud ?		arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized	bacterium briefly cloned comamonas deduced degrading depolymerase depolymerases distinguished encodes exfoliatus gram homologies homology hydrolysis hydrolyze hydroxyalkanoate hydroxybutyrate hydroxyoctanoate isolate k10 pha phaz pho poly sp streptomyces subgroup utilize
Tagcloud (Difference) ?		arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized	bacterium briefly cloned comamonas deduced degrading depolymerase depolymerases distinguished encodes exfoliatus gram homologies homology hydrolysis hydrolyze hydroxyalkanoate hydroxybutyrate hydroxyoctanoate isolate k10 pha phaz pho poly sp streptomyces subgroup utilize
Tagcloud (Intersection) ?