CHORDC1 and PPP5C

Number of citations of the paper that reports this interaction (PMID 16083881)
13

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, two hybrid)

		CHORDC1	PPP5C
Gene Name		cysteine and histidine-rich domain (CHORD) containing 1	protein phosphatase 5, catalytic subunit
Image
Gene Ontology Annotations	Cellular Component	Cellular_component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Zinc Ion Binding Hsp90 Protein Binding	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Signal Transducer Activity Protein Binding Lipid Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Centrosome Duplication Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity	DNA Repair Transcription, DNA-templated Protein Dephosphorylation Mitotic Nuclear Division Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Morphine Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: HSP90AB1 PAK1 PPP5C XPO1	22 interactors: APP CDC16 CDC27 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A MAP3K5 MAP3K7 MAPT PPP2R1A PPP2R3A
Entrez ID		26973	5536
HPRD ID		05072	02805
Ensembl ID			ENSG00000011485
Uniprot IDs		Q9UHD1	B7Z1I1 P53041
PDB IDs		2YRT	1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69
Enriched GO Terms of Interacting Partners?		Response To Osmotic Stress Response To Organic Substance Regulation Of Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Signaling Regulation Of Nucleocytoplasmic Transport Ribosomal Small Subunit Export From Nucleus Regulation Of Intracellular Protein Transport Phagocytosis Fc Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Positive Regulation Of Protein Serine/threonine Kinase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Response To Stress Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-T11 Phosphorylation Ribosomal Large Subunit Export From Nucleus Immune Response-regulating Cell Surface Receptor Signaling Pathway Ribosomal Subunit Export From Nucleus Regulation Of Protein Catabolic Process Axon Guidance Contact Inhibition Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Regulation Of Intracellular Transport Positive Regulation Of Protein Import Into Nucleus, Translocation Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Signal Transduction Positive Regulation Of Kinase Activity Regulation Of Cytoskeleton Organization Positive Regulation Of Cell Size Axonogenesis Regulation Of Protein Metabolic Process Regulation Of Protein Import Into Nucleus, Translocation Positive Regulation Of Transferase Activity Signaling Axon Development Cell Communication Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Interferon-gamma-mediated Signaling Pathway Chemotaxis Regulation Of Response To Interferon-gamma Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hyperosmotic Response Regulation Of Protein Transport Neuron Projection Morphogenesis Positive Regulation Of Immune Response	Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Cell Death Death Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Signal Transduction Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Catalytic Activity Intracellular Receptor Signaling Pathway Activation Of MAPKK Activity Positive Regulation Of Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Catabolic Process Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Metal Ion Homeostasis Positive Regulation Of Phospholipase Activity Cellular Protein Metabolic Process Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Phospholipase Activity Chemical Homeostasis Positive Regulation Of Lipase Activity Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Intracellular Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway
Tagcloud ?		aiming aip alignment boar brms1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Difference) ?		aiming aip alignment boar brms1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Intersection) ?