NAIP and HPCA

Number of citations of the paper that reports this interaction (PMID 10899114)
15

Data Source:
HPRD (two hybrid, in vitro)

		NAIP	HPCA
Gene Name		NLR family, apoptosis inhibitory protein	hippocalcin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Spindle Microtubule Basolateral Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding	Actin Binding Calcium Ion Binding
	Biological Process	Inflammatory Response Nervous System Development Regulation Of Signal Transduction Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Mitotic Spindle Assembly Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Inner Ear Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CASP9 HPCA MAP3K7	2 interactors: NAIP NMT1
Entrez ID		4671	3208
HPRD ID		09049	00811
Ensembl ID		ENSG00000249437	ENSG00000121905
Uniprot IDs		B7ZLE8 E7EQW0 Q13075	P84074
PDB IDs		2VM5
Enriched GO Terms of Interacting Partners?		Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Glial Cell Apoptotic Process Immune Response-regulating Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Response To Cobalt Ion Cellular Response To Growth Factor Stimulus I-kappaB Phosphorylation Negative Regulation Of Necroptotic Process Response To Growth Factor Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Positive Regulation Of T Cell Cytokine Production Platelet Formation Platelet Morphogenesis Regulation Of Necrotic Cell Death Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production Innate Immune Response Activation Of NF-kappaB-inducing Kinase Activity Cellular Response To Dexamethasone Stimulus Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Response To Dexamethasone Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-2 Production Apoptotic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Programmed Cell Death Regulation Of NIK/NF-kappaB Signaling System Development Cell Death Anatomical Structure Formation Involved In Morphogenesis Histone H3 Acetylation Death Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Glucocorticoid Stimulus Toll-like Receptor 5 Signaling Pathway Cellular Response To Corticosteroid Stimulus Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Antibiotic Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway	N-terminal Peptidyl-glycine N-myristoylation N-terminal Protein Myristoylation Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Myristoylation Apoptotic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Programmed Cell Death Cell Death Death N-terminal Protein Amino Acid Modification Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Mitochondrion Organization Phototransduction, Visible Light Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Detection Of Visible Light Cellular Response To Light Stimulus Regulation Of Mitochondrion Organization Phototransduction Detection Of Light Stimulus Protein Lipidation Lipoprotein Biosynthetic Process Cellular Response To Radiation Regulation Of Signal Transduction Lipoprotein Metabolic Process Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Negative Regulation Of Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Signaling Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Neuron Death
Tagcloud ?		5q13 bacs bacterium ccnb1 chosen contig copy flanking hope inherited intricate legionella lgn1 map1b mapped maps muscular p1s pathogenicity pneumophila recessively simpler sma smas smn subcloning syntenic uncharacterized yac	accumulates dtg generating hete hi hpete hyperplasia intraneoplasia lipoxygenase lost lox2 manifest myc nhp pc3 peroxidizing pin prominently prostate prostates prostatic rb1cc1 reciprocal rwpe senescence senescing suppressive surprisingly
Tagcloud (Difference) ?		5q13 bacs bacterium ccnb1 chosen contig copy flanking hope inherited intricate legionella lgn1 map1b mapped maps muscular p1s pathogenicity pneumophila recessively simpler sma smas smn subcloning syntenic uncharacterized yac	accumulates dtg generating hete hi hpete hyperplasia intraneoplasia lipoxygenase lost lox2 manifest myc nhp pc3 peroxidizing pin prominently prostate prostates prostatic rb1cc1 reciprocal rwpe senescence senescing suppressive surprisingly
Tagcloud (Intersection) ?