NAIP and HPCA

Number of citations of the paper that reports this interaction (PubMedID 10899114)
50

Data Source:
HPRD (two hybrid, in vitro)

		NAIP	HPCA
Description		NLR family apoptosis inhibitory protein	hippocalcin
Image
GO Annotations	Cellular Component	Cytoplasm Basolateral Plasma Membrane Canonical Inflammasome Complex IPAF Inflammasome Complex	Cytoplasm Cytosol Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Postsynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding Cysteine-type Endopeptidase Inhibitor Activity Protein Binding ATP Binding Peptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Protein Serine/threonine Kinase Binding	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Pattern Recognition Receptor Signaling Pathway Immune System Process Apoptotic Process Inflammatory Response Nervous System Development Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Detection Of Bacterium Positive Regulation Of Interleukin-1 Beta Production Defense Response To Bacterium Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Positive Regulation Of JNK Cascade Icosanoid Biosynthetic Process Positive Regulation Of Inflammatory Response Pyroptotic Inflammatory Response	Regulation Of Signal Transduction Calcium-mediated Signaling Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Response To Aroclor 1254 Cellular Response To L-glutamate
Pathways
Drugs
Diseases		Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS			Daytime nap ( 33568662)
Interacting Genes		3 interacting genes: CASP9 HPCA MAP3K7	17 interacting genes: AP2B1 C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2
Entrez ID		4671	3208
HPRD ID		09049	00811
Ensembl ID		ENSG00000249437	ENSG00000121905
Uniprot IDs		A0A0G2JNC7 A0A0G2JS53 B7ZLE8 Q13075	P84074
PDB IDs		2VM5 8FVU	5G4P 5G58 5M6C 7OWM
Enriched GO Terms of Interacting Partners?		Response To Anesthetic Apoptosome Response To Hypoxia Glial Cell Apoptotic Process Response To Ketone Response To Oxygen Levels Response To Indole-3-methanol Intracellular Signal Transduction Response To Decreased Oxygen Levels Response To Metal Ion Caspase Complex Cellular Response To Oxygen-containing Compound Signal Transduction In Response To DNA Damage Identical Protein Binding Cellular Response To Hormone Stimulus Response To Aroclor 1254 Dendritic Spine Head Response To Ketamine I-kappaB Phosphorylation Interleukin-17A-mediated Signaling Pathway Linear Polyubiquitin Binding MAP Kinase Kinase Kinase Kinase Activity Histone Kinase Activity Positive Regulation Of CGAS/STING Signaling Pathway Interleukin-33-mediated Signaling Pathway Cellular Response To L-glutamate Protein Kinase Binding Response To Cobalt Ion Fibroblast Apoptotic Process Cellular Response To Electrical Stimulus Positive Regulation Of Cell Size Type II Transforming Growth Factor Beta Receptor Binding Positive Regulation Of JUN Kinase Activity Anoikis TRIF-dependent Toll-like Receptor Signaling Pathway ATAC Complex MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Voltage-gated Calcium Channel Activity MyD88-dependent Toll-like Receptor Signaling Pathway MAP Kinase Activity Cellular Response To Angiotensin Positive Regulation Of Execution Phase Of Apoptosis Response To L-glutamate Stimulatory C-type Lectin Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Cellular Response To Lectin Platelet Formation Response To Hormone	Phosphocreatine Biosynthetic Process Creatine Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?