MYF6 and ID1

Number of citations of the paper that reports this interaction (PubMedID 9242638)
0

Data Source:
HPRD (two hybrid, in vivo)

		MYF6	ID1
Description		myogenic factor 6	inhibitor of DNA binding 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Mitotic Spindle RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity
	Biological Process	Somitogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Skeletal Muscle Tissue Development Tissue Development Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Skeletal Muscle Tissue Regeneration Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Positive Regulation Of Skeletal Muscle Fiber Development Muscle Tissue Morphogenesis	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Endothelial Cell Morphogenesis Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Heart Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation BMP Signaling Pathway Protein Destabilization Collagen Metabolic Process Regulation Of MAPK Cascade Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of DNA-templated Transcription Response To Antibiotic Rhythmic Process Blood Vessel Morphogenesis Lung Morphogenesis Lung Vasculature Development Endothelial Cell Apoptotic Process Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Myogenesis Myogenesis TGFBR3 expression	Oncogene Induced Senescence NGF-stimulated transcription Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Diseases		Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
GWAS			Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		10 interacting genes: CALM1 CALM2 CALM3 CSRP3 ID1 ID2 ID3 LAMTOR5 TCF12 TCF3	26 interacting genes: APPL1 ASCL3 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MSGN1 MYF5 MYF6 MYOD1 MYOG PSMD4 RNF4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4 TRIM55 TRIM63 UBC
Entrez ID		4618	3397
HPRD ID		01169	08980
Ensembl ID		ENSG00000111046	ENSG00000125968
Uniprot IDs		P23409	P41134
PDB IDs
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Sarcomere Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Protein Dimerization Activity Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Catalytic Complex Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol BHLH Transcription Factor Binding Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Transmembrane Transporter Binding Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Protein-containing Complex Transcription Regulator Inhibitor Activity Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of DNA-binding Transcription Factor Activity Sperm Midpiece Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Regulation Of Heart Contraction Long-term Synaptic Potentiation Cell Cycle G2/M Phase Transition Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Neural Nucleus Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Detection Of Stimulus Regulation Of Blood Circulation	Positive Regulation Of Transcription By RNA Polymerase II E-box Binding Protein Dimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Macromolecule Metabolic Process DNA Binding Chromatin Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Muscle Cell Fate Commitment Positive Regulation Of Metabolic Process Cell Fate Commitment Sequence-specific Double-stranded DNA Binding Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulator Complex Regulation Of Skeletal Muscle Tissue Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Anterior/posterior Pattern Specification Regulation Of Striated Muscle Tissue Development Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Muscle Organ Development Regulation Of Myotube Differentiation Positive Regulation Of Myoblast Differentiation Regulation Of Metabolic Process Somitogenesis Animal Organ Development Cell Differentiation Regulation Of Macromolecule Metabolic Process Tissue Regeneration Segmentation Muscle Organ Development
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