MYF6

Description		myogenic factor 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Mitotic Spindle RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Somitogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Skeletal Muscle Tissue Development Tissue Development Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Skeletal Muscle Tissue Regeneration Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Positive Regulation Of Skeletal Muscle Fiber Development Muscle Tissue Morphogenesis
Pathways		Myogenesis Myogenesis TGFBR3 expression
Drugs
Diseases		Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
GWAS
Interacting Genes		10 interacting genes: CALM1 CALM2 CALM3 CSRP3 ID1 ID2 ID3 LAMTOR5 TCF12 TCF3
Entrez ID		4618
HPRD ID		01169
Ensembl ID		ENSG00000111046
Uniprot IDs		P23409
PDB IDs
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Sarcomere Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Protein Dimerization Activity Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Catalytic Complex Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol BHLH Transcription Factor Binding Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Transmembrane Transporter Binding Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Protein-containing Complex Transcription Regulator Inhibitor Activity Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of DNA-binding Transcription Factor Activity Sperm Midpiece Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Regulation Of Heart Contraction Long-term Synaptic Potentiation Cell Cycle G2/M Phase Transition Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Neural Nucleus Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Detection Of Stimulus Regulation Of Blood Circulation
Tagcloud ?