RTL8B and PEG10

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RTL8B	PEG10
Description		retrotransposon Gag like 8B	paternally expressed 10
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Vesicle
	Molecular Function	Protein Binding	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process		Apoptotic Process Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Transport Protein Homooligomerization Viral Translational Frameshifting Vesicle-mediated Intercellular Transport
Pathways
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: ALAS1 CCDC102B KRT13 PEG10 RIN3 SDCBP SPG21 TADA2A UBC UBQLN1 UBQLN2	21 interacting genes: CALCOCO2 CLIP4 EXOSC5 LAMTOR5 LNX2 MAPT NXF1 RAB3IP RBFOX2 RNF181 RTL8A RTL8B SIAH1 SIAH2 SMCHD1 SNRPA SNW1 TOLLIP UBC VPS26C ZNF512B
Entrez ID		441518	23089
HPRD ID		19134	15117
Ensembl ID		ENSG00000212747	ENSG00000242265
Uniprot IDs		Q17RB0	A0A087WZG9 Q86TG7
PDB IDs			7LGA
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Receptor Internalization Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Endocytosis Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of ERAD Pathway Negative Regulation Of Transport Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Interleukin-5 Receptor Complex Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Mast Cell Chemotaxis Cytosol Regulation Of Endocytosis 5-aminolevulinate Synthase Activity Response To Nickel Cation Interleukin-5 Receptor Binding Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Extracellular Vesicle Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Vesicle-mediated Intercellular Transport Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Response To Platinum Ion Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process Response To Herbicide Positive Regulation Of Proteolysis Involved In Protein Catabolic Process	Amyloid Fibril Formation Ubiquitin Conjugating Enzyme Binding
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