PEG10 and RTL8A

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PEG10	RTL8A
Description		paternally expressed 10	retrotransposon Gag like 8A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Vesicle
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Apoptotic Process Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Transport Protein Homooligomerization Viral Translational Frameshifting Vesicle-mediated Intercellular Transport
Pathways
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: CALCOCO2 CLIP4 EXOSC5 LAMTOR5 LNX2 MAPT NXF1 RAB3IP RBFOX2 RNF181 RTL8A RTL8B SIAH1 SIAH2 SMCHD1 SNRPA SNW1 TOLLIP UBC VPS26C ZNF512B	6 interacting genes: APP CCDC102B HSPB3 PEG10 UBQLN1 UBQLN2
Entrez ID		23089	26071
HPRD ID		15117	06485
Ensembl ID		ENSG00000242265	ENSG00000203950
Uniprot IDs		A0A087WZG9 Q86TG7	Q9BWD3
PDB IDs		7LGA
Enriched GO Terms of Interacting Partners?		Amyloid Fibril Formation Ubiquitin Conjugating Enzyme Binding	Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Binding Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Receptor Internalization Autophagosome Negative Regulation Of Store-operated Calcium Channel Activity Autophagosome Assembly ERAD Pathway Acetylcholine Receptor Activator Activity Positive Regulation Of Catabolic Process Lipoprotein Particle Regulation Of Cellular Response To Stress Positive Regulation Of Protein Import Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Vesicle-mediated Intercellular Transport Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Clathrin-dependent Endocytosis Vacuole Organization
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