MLN and MLNR

Number of citations of the paper that reports this interaction (PMID 10381885)
30

Data Source:
HPRD (in vitro, in vivo)

		MLN	MLNR
Gene Name		motilin	motilin receptor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Receptor Binding Hormone Activity	G-protein Coupled Receptor Activity Growth Hormone-releasing Hormone Receptor Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling	G-protein Coupled Receptor Signaling Pathway Digestion
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Obesity (extreme) ( 19553259) Obesity-related traits ( 23251661) Phosphorus levels ( 20558539)
Protein-Protein Interactions		1 interactors: MLNR	4 interactors: GHRHR GHRL GPRASP1 MLN
Entrez ID		4295	2862
HPRD ID		15931	04197
Ensembl ID		ENSG00000096395	ENSG00000102539
Uniprot IDs		P12872	O43193
PDB IDs		1LBJ
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Growth Hormone Secretion Regulation Of Growth Hormone Secretion Growth Hormone Secretion Positive Regulation Of Multicellular Organism Growth Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Hormone Secretion Hormone Transport Peptide Transport Regulation Of Multicellular Organism Growth Positive Regulation Of Hormone Secretion Cortisol Secretion Amide Transport Cell-cell Signaling Positive Regulation Of Developmental Growth Somatotropin Secreting Cell Development Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep G-protein Coupled Receptor Catabolic Process G-protein Coupled Receptor Signaling Pathway Response To Estrogen Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Peptide Hormone Secretion Positive Regulation Of Growth Positive Regulation Of Cortisol Secretion Positive Regulation Of Corticotropin Secretion Positive Regulation Of Appetite Regulation Of Hormone Secretion Regulation Of Hormone Levels Regulation Of Corticotropin Secretion Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Somatotropin Secreting Cell Differentiation Regulation Of Developmental Growth Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Secretion Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Adult Feeding Behavior Gastric Acid Secretion Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Establishment Of Localization In Cell Response To Steroid Hormone Adenohypophysis Development Negative Regulation Of Interleukin-1 Beta Production Secretion By Cell Regulation Of Circadian Sleep/wake Cycle, Sleep
Tagcloud ?		absorptive bowel crypt develops gastrostomy gn infused intestine isocaloric isograft isografts isonitrogenous jejunal jejunum leave lewis mesenteric morphometric mucosal orthotopic osmotic parenteral polymeric pumps subcutaneously transected transection transplanted villus
Tagcloud (Difference) ?		absorptive bowel crypt develops gastrostomy gn infused intestine isocaloric isograft isografts isonitrogenous jejunal jejunum leave lewis mesenteric morphometric mucosal orthotopic osmotic parenteral polymeric pumps subcutaneously transected transection transplanted villus
Tagcloud (Intersection) ?