ASAH1 and CAMK1D

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ASAH1	CAMK1D
Gene Name		N-acylsphingosine amidohydrolase (acid ceramidase) 1	calcium/calmodulin-dependent protein kinase ID
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Lumen Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Catalytic Activity Ceramidase Activity	Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding
	Biological Process	Sphingolipid Metabolic Process Ceramide Metabolic Process Glycosphingolipid Metabolic Process Response To Organic Substance Lung Development Small Molecule Metabolic Process	Protein Phosphorylation Inflammatory Response Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism
Drugs
Diseases
GWAS		Obesity ( 21552555)	Anorexia nervosa ( 23568457) Eating disorders ( 23568457) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Type 2 diabetes ( 18372903 20862305)
Protein-Protein Interactions		5 interactors: CAMK1D SETDB1 SMPD1 SRPK1 TSC22D1	11 interactors: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG NEDD4 NEDD4L POT1 TNFSF13
Entrez ID		427	57118
HPRD ID		01969	06409
Ensembl ID		ENSG00000104763	ENSG00000183049
Uniprot IDs		A8K0B6 E7EMM4 Q13510 Q53H01	Q5SQQ7 Q8IU85
PDB IDs			2JC6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Sphingomyelin Catabolic Process Positive Regulation Of Respiratory Burst Sperm Chromatin Condensation Histone H3-K9 Trimethylation Regulation Of Apoptotic Process Regulation Of Respiratory Burst Regulation Of Cell Death Sphingomyelin Metabolic Process Regulation Of Metabolic Process Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Protein Dephosphorylation Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation Positive Regulation Of Viral Genome Replication Positive Regulation Of Neutrophil Chemotaxis Regulation Of RNA Metabolic Process Peptidyl-lysine Trimethylation Positive Regulation Of Granulocyte Chemotaxis Phospholipid Catabolic Process Blastocyst Growth Sphingolipid Catabolic Process Spermatid Nucleus Differentiation Regulation Of Neutrophil Chemotaxis Regulation Of Neutrophil Migration Membrane Lipid Catabolic Process	Protein Monoubiquitination Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Polyubiquitination Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transferase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Cell Cycle Phase Transition Regulation Of Kinase Activity Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Regulation Of Sodium Ion Transport Response To Light Stimulus Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of DNA Strand Elongation Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Protein Catabolic Process Protein Metabolic Process Regulation Of Synapse Structure Or Activity Cellular Response To Light Stimulus Negative Regulation Of Ion Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Response To Radiation Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Cellular Metabolic Process Modification-dependent Protein Catabolic Process Mitochondrial Protein Catabolic Process Telomere Formation Via Telomerase
Tagcloud ?		adjuvant apoptotic best breast cancers ceramidase ceramide converting dcis even generally good improved invasive luminal mainly metabolism moreover overexpressed phenotype pre pro prognosis recurrences sphingolipid sphingosine subtype subtypes valuable
Tagcloud (Difference) ?		adjuvant apoptotic best breast cancers ceramidase ceramide converting dcis even generally good improved invasive luminal mainly metabolism moreover overexpressed phenotype pre pro prognosis recurrences sphingolipid sphingosine subtype subtypes valuable
Tagcloud (Intersection) ?