Wiki-Pi
About
Search
People
Updates
Search
KITLG and CSF2
Number of citations of the paper that reports this interaction (PubMedID
12421569
)
0
Data Source:
HPRD
(in vivo)
KITLG
CSF2
Description
KIT ligand
colony stimulating factor 2
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Cytoskeleton
Plasma Membrane
Membrane
Lamellipodium
Filopodium
Cell Projection
Extracellular Region
Extracellular Space
Plasma Membrane
Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
Molecular Function
Cytokine Activity
Stem Cell Factor Receptor Binding
Protein Binding
Growth Factor Activity
Cytokine Activity
Granulocyte Macrophage Colony-stimulating Factor Receptor Binding
Protein Binding
Growth Factor Activity
Biological Process
Ovarian Follicle Development
Neural Crest Cell Migration
Hematopoietic Progenitor Cell Differentiation
Myeloid Leukocyte Differentiation
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Myeloid Leukocyte Differentiation
Developmental Process Involved In Reproduction
Apoptotic Process
Cell Adhesion
Ras Protein Signal Transduction
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Male Gonad Development
Mast Cell Apoptotic Process
Negative Regulation Of Mast Cell Apoptotic Process
Embryonic Hemopoiesis
Ectopic Germ Cell Programmed Cell Death
T Cell Proliferation
Positive Regulation Of T Cell Proliferation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Melanocyte Differentiation
Positive Regulation Of Ras Protein Signal Transduction
Animal Organ Development
Mast Cell Proliferation
Positive Regulation Of Mast Cell Proliferation
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Melanocyte Migration
Mast Cell Migration
Positive Regulation Of Hematopoietic Progenitor Cell Differentiation
Positive Regulation Of Hematopoietic Stem Cell Proliferation
Histamine Secretion
Embryonic Placenta Development
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Myeloid Cell Differentiation
Neutrophil Differentiation
Monocyte Differentiation
Macrophage Differentiation
Positive Regulation Of Cell Migration
Positive Regulation Of Interleukin-23 Production
Response To Silicon Dioxide
Response To Fluid Shear Stress
Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway
Epithelial Fluid Transport
Regulation Of Cell Population Proliferation
Myeloid Dendritic Cell Differentiation
Regulation Of Circadian Sleep/wake Cycle, Sleep
Negative Regulation Of DNA-templated Transcription
Regulation Of Developmental Process
Positive Regulation Of Leukocyte Proliferation
Cellular Response To Lipopolysaccharide
Positive Regulation Of Podosome Assembly
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Dendritic Cell Differentiation
Cell Surface Receptor Signaling Pathway Via STAT
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Interleukin-3, Interleukin-5 and GM-CSF signaling
RAF/MAP kinase cascade
Interleukin-10 signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
Interleukin receptor SHC signaling
Drugs
KB002
Diseases
Familial progressive hyperpigmentation
GWAS
Aspartate aminotransferase levels (
33547301
)
Blond vs non-blond hair color (
26184321
)
Blond vs. brown hair color (
17952075
)
Blond vs. brown/black hair color (
30531825
)
Brown vs. black hair color (
30531825
)
Brown vs. non-brown hair color (
26184321
)
Facial skin colour (CIELAB index b* value) (
34648798
)
Facial skin colour (CIELAB index L* value) (
34648798
)
Hair color (
23548203
29662168
)
Light vs. dark hair color (
26184321
)
Mean corpuscular volume (
32888494
)
Nevus count (
30429480
)
Red blood cell traits (
23222517
)
Testicular cancer (
19483682
)
Testicular germ cell cancer (
20543847
)
Testicular germ cell tumor (
28604728
28604732
23666240
23666239
19483681
)
Youthful appearance (self-reported) (
32339537
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
23128233
28067908
)
Rheumatoid arthritis (
22446963
24390342
30423114
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
9 interacting genes:
CLEC11A
CMA1
CSF2
EPOR
FLT3LG
KIT
PIK3CD
S100A6
UBE2V1
9 interacting genes:
CSF2RA
CSF2RB
IL3RA
KITLG
MEOX2
PRG2
S100A6
S100P
SDC2
Entrez ID
4254
1437
HPRD ID
01698
00734
Ensembl ID
ENSG00000049130
ENSG00000164400
Uniprot IDs
P21583
P04141
PDB IDs
1EXZ
1SCF
2E9W
8DFM
8DFP
8DFQ
1CSG
2GMF
4NKQ
4RS1
5C7X
5D70
5D71
5D72
6BFQ
6BFS
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Population Proliferation
Mast Cell Differentiation
Mast Cell Chemotaxis
Mast Cell Migration
Erythropoietin-mediated Signaling Pathway
Mononuclear Cell Differentiation
Leukocyte Differentiation
B Cell Differentiation
Regulation Of Cell Population Proliferation
Myeloid Leukocyte Differentiation
Embryonic Hemopoiesis
Embryonic Organ Development
Positive Regulation Of Leukocyte Proliferation
Mast Cell Degranulation
B Cell Activation
Leukocyte Activation
Dendritic Cell Differentiation
Leukocyte Degranulation
Extracellular Region
Cell Activation
Lymphocyte Differentiation
Myeloid Cell Differentiation
Regulation Of Leukocyte Proliferation
Developmental Process
Extracellular Space
Granulocyte Macrophage Colony-stimulating Factor Receptor Binding
Erythropoietin Receptor Activity
Lysosome Localization
Positive Regulation Of Pyloric Antrum Smooth Muscle Contraction
Melanocyte Adhesion
Stem Cell Factor Receptor Activity
Positive Regulation Of Colon Smooth Muscle Contraction
Positive Regulation Of Multicellular Organismal Process
Cytokine-mediated Signaling Pathway
Error-free Postreplication DNA Repair
Basement Membrane Disassembly
Signal Transduction
Lymphocyte Activation
Regulated Exocytosis
Cytoplasmic Side Of Plasma Membrane
Kit Signaling Pathway
Positive Regulation Of Small Intestine Smooth Muscle Contraction
Melanocyte Migration
Natural Killer Cell Chemotaxis
UBC13-MMS2 Complex
Positive Regulation Of Cytokine Production
Secretion
Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway
Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
Response To Silicon Dioxide
Interleukin-3 Receptor Activity
Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway
Regulation Of Macrophage Cytokine Production
Cytokine Receptor Activity
External Side Of Plasma Membrane
Interleukin-3-mediated Signaling Pathway
Cellular Response To Interleukin-3
Extracellular Matrix
Signaling Receptor Activity
Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Macrophage Cytokine Production
Cytokine-mediated Signaling Pathway
Positive Regulation Of Leukocyte Proliferation
Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response
Cytokine Binding
Positive Regulation Of Bone Mineralization
Translation Termination Factor Activity
Cytoplasmic Translational Termination
Regulation Of Production Of Molecular Mediator Of Immune Response
Leukocyte Apoptotic Process
Positive Regulation Of Biomineral Tissue Development
Immune System Process
Positive Regulation Of Ossification
Neural Crest Cell Migration
Mesenchymal Cell Migration
Positive Regulation Of Cytokine Production
Positive Regulation Of Cell Population Proliferation
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?