MAZ and BPTF

Number of citations of the paper that reports this interaction (PubMedID 15379550)
56

Data Source:
BioGRID (pull down, two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		MAZ	BPTF
Description		MYC associated zinc finger protein	bromodomain PHD finger transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm NURF Complex Dendrite Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome ATPase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding ATP-dependent Activity, Acting On DNA Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of DNA-templated Transcription Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Embryonic Placenta Development Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Endoderm Development Anterior/posterior Pattern Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Nerve Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Multiple sclerosis ( 27386562)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Alanine aminotransferase levels ( 33547301) Alcohol dependence symptom count ( 27151647) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) EGFR mutation-positive lung adenocarcinoma ( 27501781) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Hand grip strength ( 29691431) HDL cholesterol ( 30275531) Height ( 31562340) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Lung adenocarcinoma ( 22797724) Lung cancer ( 23143601) Macular thickness ( 30535121) Metabolic syndrome ( 31589552) Neutrophil percentage of granulocytes ( 27863252) Non-small cell lung cancer ( 31326317) Psoriasis ( 25854761) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Sum eosinophil basophil counts ( 27863252) Triglyceride levels ( 32154731 32203549 33339817) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: BPTF CSNK2A1 DCC DMRTB1 EHMT2 KRT31 KRTAP10-9 OGT PICK1 RBPMS	10 interacting genes: H3-3A H3-4 H4C9 KEAP1 MAZ NFE2L2 SMAD2 SMAD3 SQSTM1 SUMO2
Entrez ID		4150	2186
HPRD ID		02999	03490
Ensembl ID		ENSG00000103495	ENSG00000171634
Uniprot IDs		P56270 Q59GP8	J3QQK4 Q12830
PDB IDs			2F6J 2F6N 2FSA 2FUI 2FUU 2RI7 3QZS 3QZT 3QZV 3UV2 5H6Y 5R4G 5R4H 5R4I 5R4J 5R4K 5R4L 5R4M 5R4N 5R4O 6AZE 6LU5 6LU6 7DMY 7DN4 7F5D 7F5E 7JT4 7K6R 7K6S 7KDW 7KDZ 7LP0 7LPK 7LRK 7LRO 7M2E 7RWN 7RWO 7RWP 7RWQ 7VD4 8AG2 8F6G 8OU2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Sin3-type Complex Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Component Organization Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Nutrient Levels Histone H3K56 Methyltransferase Activity	Ubiquitin Protein Ligase Binding Paraxial Mesoderm Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mesoderm Morphogenesis SMAD Protein Complex Pericardium Development Trophoblast Cell Migration Heteromeric SMAD Protein Complex Nucleoplasm Structural Constituent Of Chromatin Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Nucleosome Assembly DNA Binding Primary MiRNA Processing Transforming Growth Factor Beta Receptor Binding Negative Regulation Of Ferroptosis Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Ferroptosis Positive Regulation Of Proteasomal Protein Catabolic Process I-SMAD Binding Nucleosome Regulation Of Protein Catabolic Process Nucleus Nucleosome Organization Inclusion Body Positive Regulation Of Proteolysis Involved In Protein Catabolic Process SMAD Protein Signal Transduction Regulation Of Cell Differentiation Response To Angiotensin Regulation Of Transcription By RNA Polymerase II Disordered Domain Specific Binding R-SMAD Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromosome, Telomeric Region Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Response To Oxidative Stress Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein-DNA Complex Assembly Endoderm Development MiRNA Processing Positive Regulation Of RNA Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?