BPTF and MAZ

Number of citations of the paper that reports this interaction (PMID 10727212)
11

Data Source:
BioGRID (pull down, two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		BPTF	MAZ
Gene Name		bromodomain PHD finger transcription factor	MYC-associated zinc finger protein (purine-binding transcription factor)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm NURF Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding DNA-dependent ATPase Activity Transcription Factor Binding Zinc Ion Binding Sequence-specific DNA Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Chromatin Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Placenta Development Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Brain Development Endoderm Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated	Transcription Initiation From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Lung adenocarcinoma ( 22797724) Lung cancer ( 23143601)
Protein-Protein Interactions		9 interactors: H3F3A HIST1H4I HIST3H3 KEAP1 MAZ NFE2L2 SMAD2 SMAD3 SQSTM1	3 interactors: BPTF CSNK2A1 DCC
Entrez ID		2186	4150
HPRD ID		03490	02999
Ensembl ID		ENSG00000171634	ENSG00000103495
Uniprot IDs		Q12830	H3BQD6 P56270 Q59GP8
PDB IDs		2F6J 2F6N 2FSA 2FUI 2FUU 2RI7 3QZS 3QZT 3QZV 3UV2
Enriched GO Terms of Interacting Partners?		Gene Silencing Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Gene Expression, Epigenetic Primary MiRNA Processing SMAD Protein Complex Assembly Paraxial Mesoderm Morphogenesis Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Chromatin Silencing At RDNA Nodal Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Embryonic Foregut Morphogenesis Foregut Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Paraxial Mesoderm Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Pericardium Development Gene Expression Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Cellular Macromolecular Complex Assembly Activin Receptor Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Chromatin Silencing DNA Replication-independent Nucleosome Assembly Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Posttranscriptional Gene Silencing Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process SMAD Protein Signal Transduction Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Transcription From RNA Polymerase II Promoter Embryonic Cranial Skeleton Morphogenesis DNA Methylation	Netrin-activated Signaling Pathway Spinal Cord Ventral Commissure Morphogenesis Dorsal/ventral Axon Guidance Anterior/posterior Axon Guidance Regulation Of Cell Growth Negative Regulation Of Collateral Sprouting Axon Guidance Nervous System Development Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Dendrite Development Regulation Of Growth Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Positive Regulation Of Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Response To Amphetamine Neuron Development Apoptotic Process Mitotic Spindle Checkpoint Central Nervous System Development Central Nervous System Projection Neuron Axonogenesis Negative Regulation Of Chromosome Segregation Programmed Cell Death System Development Cell Death Death Cell Morphogenesis Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Response To Amine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Mitotic Metaphase/anaphase Transition Neuron Differentiation Regulation Of RNA Metabolic Process Cell Projection Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chaperone-mediated Protein Folding Negative Regulation Of Axonogenesis Locomotion Multicellular Organismal Development Central Nervous System Neuron Axonogenesis Positive Regulation Of Signal Transduction Negative Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		13q33 col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	1a 1b begin commitment construct dnase encodes erythroid ets gata helix hypersensitive inactivity joint lineage lineages mast megakaryocytic motifs multipotent nonexpressing progenitors promoter reflected repressed restricted scl transactivate weakly
Tagcloud (Difference) ?		13q33 col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	1a 1b begin commitment construct dnase encodes erythroid gata helix hypersensitive inactivity joint lineage lineages mast megakaryocytic motifs multipotent nonexpressing progenitors promoter reflected repressed restricted scl transactivate weakly
Tagcloud (Intersection) ?		ets