C10orf55 and GCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C10orf55	GCA
Description		chromosome 10 putative open reading frame 55	grancalcin
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Cytoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		Membrane Fusion
Pathways			Neutrophil degranulation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Multiple sclerosis ( 24076602) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Systemic lupus erythematosus ( 28714469) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Blood protein levels ( 30072576)
Interacting Genes		60 interacting genes: ATXN1 BOLA2 BOLA2B CRYBA2 DTX2 FAM168A FAM222B FNDC3B FOXH1 GCA HNF1B HNRNPF HSF4 INCA1 KRTAP15-1 KRTAP6-2 LENG8 LIMS3 LIMS4 MBLAC1 MGAT5B MYOZ3 NRF1 NXF1 OTX1 PFDN5 PITX1 PLEKHB1 PLSCR3 POGZ PRR20A PRR20B PRR20C PRR20D PRR20E RAMAC RBM24 RBM47 RBPMS RBPMS2 ROR2 SAXO4 SMUG1 SNRPB SOHLH1 SOX10 TBX6 TENT5B TENT5D TIAL1 TLE5 TP53BP1 UBAP2 UFSP1 VENTX VEZF1 WWOX YPEL3 ZC3H10 ZNF76	15 interacting genes: ABHD11 ATXN1 BPIFA1 C10orf55 CALCOCO2 CSTPP1 GSTO2 LCP1 MAGEA8 PSMB4 RBFOX1 SRI TRAF1 TRAF2 YPEL3
Entrez ID		414236	25801
HPRD ID		16580	06122
Ensembl ID		ENSG00000222047	ENSG00000115271
Uniprot IDs			B7Z322 H7BXD5 P28676
PDB IDs			1F4O 1F4Q 1K94 1K95
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of RNA Metabolic Process Regulation Of RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA CDS Binding MRNA Stabilization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of MRNA Metabolic Process [2Fe-2S] Cluster Assembly DNA Binding Regulation Of MRNA Splicing, Via Spliceosome Poly(A) RNA Polymerase Activity Iron-sulfur Cluster Assembly Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Nuclear Inclusion Body Pre-mRNA Intronic Binding Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of Gene Expression MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Embryonic Digestive Tract Morphogenesis Protein Binding RNA Binding	Thioesterase Binding
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