MIR34C and STRBP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR34C	STRBP
Description		microRNA 34c	spermatid perinuclear RNA binding protein
Image		No pdb structure
GO Annotations	Cellular Component		Manchette Nucleus Cytoplasm Microtubule Cytoskeleton
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Microtubule Binding Tubulin Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Connective Tissue Replacement	Spermatogenesis Spermatid Development Mechanosensory Behavior Cell Differentiation Cell Motility
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) Waist-hip index ( 34021172)	Birth weight ( 27680694) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 31217584 31562340) Lymphocyte count ( 32888494)
Interacting Genes		78 interacting genes: AIMP1 AIMP2 APOBEC3B C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 XRN1 YBX1 YBX2 YBX3 ZNF346 ZNF385A	59 interacting genes: ADARB1 ARNT CAMK2G DAB1 EIF2AK2 HMGXB4 LRRK2 MAP4 MIR1-1 MIR1-2 MIR106A MIR122 MIR128-2 MIR138-1 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-2 MIR199A1 MIR199A2 MIR19A MIR200A MIR200B MIR200C MIR214 MIR221 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR429 MIR7-1 MIR7-3 MIR9-1 MIR9-3 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NEIL3 RBFOX1 RBPMS RBPMS2 STAU1 THAP1 ZMAT4 ZNF346
Entrez ID		407042	55342
HPRD ID			10257
Ensembl ID		ENSG00000207562	ENSG00000165209
Uniprot IDs			A0A0S2Z5K8 Q96SI9 V9HWK4
PDB IDs			2DMY
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Binding Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Macromolecule Metabolic Process Regulation Of Translation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Nucleoplasm Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Regulation Of Gene Expression Negative Regulation Of Translation Catalytic Step 2 Spliceosome Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process MiRNA Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization Regulation Of Primary Metabolic Process MRNA Stabilization Cytoplasmic Stress Granule Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Positive Regulation Of Gene Expression Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Regulation Of RNA Stability Ligase Activity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cytoplasmic Translation	Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of Gene Expression Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Negative Regulation Of Locomotion RNA Destabilization Positive Regulation Of MRNA Catabolic Process Extracellular Vesicle Regulation Of Macromolecule Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Protein Metabolic Process Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Translation Regulation Of Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Locomotion Regulation Of Anatomical Structure Morphogenesis Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration
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