MIR34C and RBMS2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR34C	RBMS2
Description		microRNA 34c	RNA binding motif single stranded interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Poly(A) Binding Poly(U) RNA Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Connective Tissue Replacement	RNA Processing
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) Waist-hip index ( 34021172)	Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Platelet count ( 29403010) Serum metabolite levels ( 23093944)
Interacting Genes		78 interacting genes: AIMP1 AIMP2 APOBEC3B C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 XRN1 YBX1 YBX2 YBX3 ZNF346 ZNF385A	22 interacting genes: DIPK1B FOXP1 MIR1-2 MIR155 MIR15B MIR16-2 MIR19A MIR19B1 MIR19B2 MIR205 MIR222 MIR29A MIR29B1 MIR34C MIR7-1 MIR7-2 MIR9-2 MIR92A2 MIR93 MIRLET7C SRPK1 UBC
Entrez ID		407042	5939
HPRD ID			03860
Ensembl ID		ENSG00000207562	ENSG00000076067
Uniprot IDs			Q15434
PDB IDs			1X4E
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Binding Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Macromolecule Metabolic Process Regulation Of Translation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Nucleoplasm Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Regulation Of Gene Expression Negative Regulation Of Translation Catalytic Step 2 Spliceosome Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process MiRNA Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization Regulation Of Primary Metabolic Process MRNA Stabilization Cytoplasmic Stress Granule Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Positive Regulation Of Gene Expression Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Regulation Of RNA Stability Ligase Activity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cytoplasmic Translation	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Extracellular Vesicle Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Cytokine Production Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Multicellular Organismal Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Macromolecule Metabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Cytokine Production Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Cell Migration MRNA Destabilization RNA Destabilization Negative Regulation Of Cell Motility Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Signal Transduction Extracellular Space Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of Muscle Cell Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Heart Growth Regulation Of Cell Migration
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