MIR29A and RBM47

Number of citations: 0 (PubMedID 28431233)
Data Source: BioGRID (unspecified method)

		MIR29A	RBM47
Name		microRNA 29a	RNA binding motif protein 47
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex
	Molecular Function	MRNA 3'-UTR Binding LncRNA Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Enzyme Binding Enzyme-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of Collagen Biosynthetic Process MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Epigenetic Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Circulating Fibrinogen Levels Positive Regulation Of Wound Healing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Alternative MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation MRNA Processing RNA Splicing Cytidine To Uridine Editing Positive Regulation Of Interleukin-10 Production Low-density Lipoprotein Particle Clearance Positive Regulation Of Type I Interferon-mediated Signaling Pathway 3'-UTR-mediated MRNA Stabilization
GWAS		Basal cell carcinoma ( 31174203 ) HDL cholesterol levels ( 30698716 ) HDL cholesterol levels in current drinkers ( 30698716 ) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 ) High density lipoprotein cholesterol levels ( 33339817 ) Keratinocyte cancer (MTAG) ( 31174203 ) Lymphocyte count ( 32888494 ) Neutrophil count ( 32888494 ) Pancreatic cancer ( 25086665 ) Red blood cell count ( 32888494 ) Triglyceride levels ( 30698716 ) Triglyceride levels in current drinkers ( 30698716 ) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 ) White blood cell count ( 32888494 )	Apolipoprotein B levels ( 32203549 ) Body mass index (change over time) ( 25133637 ) Carotid intima media thickness x smoking interaction ( 32117412 ) Diastolic blood pressure ( 27618447 ) Hypertension ( 27618447 ) Monocyte count ( 32888494 ) Mosquito bite size ( 28199695 ) Systolic blood pressure ( 27618447 ) Total cholesterol levels ( 30275531 ) Triglyceride levels in HIV infection ( 33109212 )
Interacting Genes		84 interacting genes: AIMP2 APOBEC3B AQR C1QBP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM47 RBMS1 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TIAL1 TRA2B TRIM25 TRIM71 UPF1 USP36 UTP20 YBX1 YBX3 ZC3H7A ZC3H7B ZNF346	17 interacting genes: C10orf55 C1orf94 CAMK2A CELF5 HIVEP1 HSFY1 MIR16-1 MIR29A MIR29B1 MIRLET7E MIRLET7F1 NUTM2F OTX2 PCBP3 PRR13 RBFOX1 ZNF385C
Entrez ID		407021	54502
HPRD ID		Not available	13373
Ensembl ID		ENSG00000284032	ENSG00000163694
Uniprot IDs		Not available	A0AV96 B7Z8Z7
PDB IDs		Not available	2DIS
GO Terms Enriched among Interactors		RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process MRNA Binding Nucleus Post-transcriptional Regulation Of Gene Expression Regulation Of RNA Splicing Ribonucleoprotein Complex MiRNA Binding Nucleoplasm MRNA 3'-UTR Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Aminoacyl-tRNA Synthetase Multienzyme Complex Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal Complex Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of RNA Stability Regulation Of Translation Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Stabilization Regulation Of MRNA Stability MRNA Stabilization Regulation Of Macromolecule Metabolic Process MiRNA Processing Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Catabolic Process Ligase Activity	MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Mesenchymal Stem Cell Proliferation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Circulating Fibrinogen Levels Regulation Of Amyloid-beta Formation MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amide Metabolic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Extracellular Vesicle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Mitochondrial Membrane Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Stem Cell Proliferation LncRNA Binding Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Collagen Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Translation Peptidyl-threonine Autophosphorylation C-rich Single-stranded DNA Binding Regulation Of Endothelial Cell Migration Negative Regulation Of Placenta Blood Vessel Development Regulation Of Collagen Metabolic Process Negative Regulation Of Intestinal Epithelial Cell Development