MIR155 and SPOUT1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR155	SPOUT1
Description		microRNA 155	SPOUT domain containing methyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Spindle Cytoskeleton Spindle Pole Centrosome Mitotic Spindle
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Protein Binding Methyltransferase Activity Transferase Activity MiRNA Binding RRNA (uridine-N3-)-methyltransferase Activity S-adenosyl-L-methionine Binding
	Biological Process	Negative Regulation Of Cytokine Production Negative Regulation Of Gene Expression MiRNA-mediated Post-transcriptional Gene Silencing	RRNA Processing Post-transcriptional Regulation Of Gene Expression Methylation MiRNA Processing Cell Division Maintenance Of Centrosome Location RRNA Base Methylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		91 interacting genes: ADARB1 APOBEC3B C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBMS2 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TRIM71 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346 ZNF385A	52 interacting genes: CSNK2B INCA1 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR34A MIR34B MIR429 MIR7-1 MIR9-1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PLK1
Entrez ID		406947	51490
HPRD ID			12935
Ensembl ID		ENSG00000283904	ENSG00000198917
Uniprot IDs			Q5T280
PDB IDs			4RG1 8QSU 8QSV 8QSW
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Nucleus Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleoplasm Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of Translation Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule MiRNA Binding Negative Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Negative Regulation Of Translation Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Regulation Of Primary Metabolic Process RNA Stabilization Regulation Of MRNA Stability MRNA Stabilization U2 SnRNP Regulation Of RNA Stability Spliceosomal Complex Assembly Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of Metabolic Process Positive Regulation Of Gene Expression Nucleolus Negative Regulation Of Macromolecule Metabolic Process Protein-RNA Complex Assembly	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Angiogenesis Regulation Of RNA Stability Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Regulation Of Angiogenesis Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Metabolic Process Regulation Of Cell Motility Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Locomotion Negative Regulation Of Developmental Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of MRNA Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration
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