FAM98B

Description		family with sequence similarity 98 member B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm TRNA-splicing Ligase Complex
	Molecular Function	RNA Binding Protein Binding Protein Methyltransferase Activity Identical Protein Binding
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Psychosis (atypical) ( 24132900) Systemic lupus erythematosus ( 24871463)
Novel Interacting Genes		2 novel interacting genes: PLCB2 STK11
Interacting Genes		21 interacting genes: CEBPA MIR106A MIR10B MIR138-1 MIR141 MIR16-1 MIR18B MIR199A2 MIR200B MIR200C MIR205 MIR222 MIR34A MIR7-3 MIR9-1 MIRLET7A1 MIRLET7A2 MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G
Entrez ID		283742
HPRD ID		08786
Ensembl ID		ENSG00000171262
Uniprot IDs		Q52LJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Locomotion Regulation Of Cell Migration Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Metabolic Process Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization RNA Destabilization Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Developmental Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of Osteoblast Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
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