FAM98B and MIRLET7A2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		FAM98B	MIRLET7A2
Description		family with sequence similarity 98 member B	microRNA let-7a-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm TRNA-splicing Ligase Complex	RISC Complex
	Molecular Function	RNA Binding Protein Binding Protein Methyltransferase Activity Identical Protein Binding
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Psychosis (atypical) ( 24132900) Systemic lupus erythematosus ( 24871463)
Interacting Genes		21 interacting genes: CEBPA MIR106A MIR10B MIR138-1 MIR141 MIR16-1 MIR18B MIR199A2 MIR200B MIR200C MIR205 MIR222 MIR34A MIR7-3 MIR9-1 MIRLET7A1 MIRLET7A2 MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G	95 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CHERP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PTCD3 PUM1 PUM2 QARS1 RARS1 RBM14 RBM17 RBM4 RTCB SAFB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		283742	406882
HPRD ID		08786
Ensembl ID		ENSG00000171262	ENSG00000198975
Uniprot IDs		Q52LJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Locomotion Regulation Of Cell Migration Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Metabolic Process Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization RNA Destabilization Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Developmental Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of Osteoblast Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Macromolecule Metabolic Process Catalytic Step 2 Spliceosome Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm Nucleus MiRNA Binding Cytoplasmic Stress Granule Regulation Of RNA Splicing Regulation Of Translation Ribonucleoprotein Complex MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Processing MiRNA Processing Negative Regulation Of MRNA Catabolic Process Regulation Of Macromolecule Metabolic Process RNA Stabilization TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process TRNA Aminoacylation MRNA Stabilization U2 SnRNP Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression CRD-mediated MRNA Stabilization
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