PTCD3 and IFITM2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PTCD3	IFITM2
Description		pentatricopeptide repeat domain 3	interferon induced transmembrane protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Cytosol Ribosome Plasma Membrane Ribonucleoprotein Complex	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Late Endosome Membrane Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process	Regulation Of Translation Mitochondrial Translation	Immune System Process Immune Response Response To Virus Response To Type II Interferon Response To Interferon-alpha Response To Interferon-beta Cellular Response To Interferon-beta Negative Regulation Of Viral Genome Replication Innate Immune Response Host-mediated Suppression Of Symbiont Invasion Defense Response To Virus Type I Interferon-mediated Signaling Pathway
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Facial emotion recognition (sad faces) ( 28608620) Pulse pressure ( 27841878) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Systolic blood pressure ( 27841878)	Autoimmune thyroid disease ( 32581359) Basophil count ( 32888494) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494 27863252) Mean platelet volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Myocardial infarction ( 33532862) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Platelet count ( 27863252 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		22 interacting genes: ATF4 BIRC7 HGS IFITM2 LNX2 LUC7L2 MIR128-2 MIR18B MIR200B MIR200C MIR205 MIR21 MIR214 MIR34B MIR34C MIR363 MIRLET7A2 MIRLET7F2 MIRLET7G MT-RNR1 TBPL1 UBE3A	4 interacting genes: KRTAP1-1 PTCD3 SLC10A1 UPF3A
Entrez ID		55037	10581
HPRD ID		08631	05718
Ensembl ID		ENSG00000132300	ENSG00000185201
Uniprot IDs		Q96EY7	Q01629
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Regulation Of Vasculature Development MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Translation Positive Regulation Of Cardiac Muscle Hypertrophy MiRNA-mediated Gene Silencing By MRNA Destabilization Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Connective Tissue Replacement Regulation Of Multicellular Organismal Development Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Connective Tissue Replacement Regulation Of Osteoblast Differentiation Negative Regulation Of Interleukin-33 Production Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Tissue Remodeling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Anatomical Structure Morphogenesis MRNA Destabilization RNA Destabilization Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Developmental Process Regulation Of Muscle System Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Metabolic Process
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