PTCD3 and IFITM2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PTCD3	IFITM2
Gene Name		pentatricopeptide repeat domain 3	interferon induced transmembrane protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RRNA Binding Ribosomal Small Subunit Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Immune Response Response To Virus Cytokine-mediated Signaling Pathway Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination	Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ATF4 HGS IFITM2 LUC7L2 RNR1 TBPL1	2 interactors: PTCD3 UPF3A
Entrez ID		55037	10581
HPRD ID		08631	05718
Ensembl ID		ENSG00000132300	ENSG00000185201
Uniprot IDs		Q96EY7	Q01629
PDB IDs
Enriched GO Terms of Interacting Partners?		DTTP Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Transcription From RNA Polymerase I Promoter Protein Targeting To Lysosome Deoxyribonucleotide Biosynthetic Process Acrosome Assembly Protein Localization To Lysosome Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Viral Entry Into Host Cell Response To Interferon-alpha Membrane Invagination Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Response To Interferon-beta Regulation Of Viral Entry Into Host Cell Protein Targeting To Vacuole Negative Regulation Of Potassium Ion Transport Negative Regulation Of JAK-STAT Cascade Deoxyribonucleoside Triphosphate Metabolic Process Cellular Response To Glucose Starvation Establishment Of Protein Localization To Vacuole Spermatid Nucleus Differentiation Negative Regulation Of Oxidative Stress-induced Cell Death Endosome To Lysosome Transport Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Vascular Endothelial Growth Factor Production Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Secretory Granule Organization	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression
Tagcloud ?		c17orf42 coincident comprising dead dhx30 dsdna elongation foci helicase hereafter hhh incompetence makes mitochondria mitochondrial motifs owing pentatricopeptide polrmt processivity purification ribonuclease rnase spt6 ss strand tefm templates transcripts	african amphotericin cholesterol compound entry exploit green impaired influenza inhibit interestingly interferon lentiviruses monkeys mostly much overcome overcomes ph primate refractory restricted siv sivagm surprisingly transmembrane viruses
Tagcloud (Difference) ?		c17orf42 coincident comprising dead dhx30 dsdna elongation foci helicase hereafter hhh incompetence makes mitochondria mitochondrial motifs owing pentatricopeptide polrmt processivity purification ribonuclease rnase spt6 ss strand tefm templates transcripts	african amphotericin cholesterol compound entry exploit green impaired influenza inhibit interestingly interferon lentiviruses monkeys mostly much overcome overcomes ph primate refractory restricted siv sivagm surprisingly transmembrane viruses
Tagcloud (Intersection) ?