LOX and SNX24

		LOX	SNX24
Description		lysyl oxidase	sorting nexin 24
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Extracellular Matrix	Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Small Molecule Binding Metal Ion Binding Molecular Adaptor Activity	Protein Binding Lipid Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Blood Vessel Development Osteoblast Differentiation Heart Development Response To Xenobiotic Stimulus Response To Hormone Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Aorta Development Ascending Aorta Development Descending Aorta Development Protein Modification Process Regulation Of Apoptotic Process Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Muscle Cell Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Protein Transport
Pathways		Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Waist circumference adjusted for body mass index ( 34021172) Youthful appearance (self-reported) ( 32339537)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Glucose homeostasis traits ( 25524916) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Plateletcrit ( 27863252) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 MRE11	3 interacting genes: POU2F1 SH3GL3 YWHAZ
Entrez ID		4015	28966
HPRD ID		01087	15413
Ensembl ID		ENSG00000113083	ENSG00000064652
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	Q9Y343
PDB IDs			4AZ9 8TBV 8TBW 8U9G
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome Nucleosome Assembly Nucleosome Organization Chromatin Remodeling Chromosome Protein-DNA Complex Assembly Chromatin Organization Innate Immune Response In Mucosa Double-stranded DNA Binding Negative Regulation Of DNA Metabolic Process Regulation Of DNA Recombination Phosphatidylinositol Phosphate Binding Mucosal Immune Response Organ Or Tissue Specific Immune Response Chromosome Condensation Nucleosomal DNA Binding Regulation Of DNA Metabolic Process Negative Regulation Of DNA Recombination Mitochondrial Double-strand Break Repair Via Homologous Recombination Nicotinamide Phosphoribosyltransferase Activity Polyprenol Biosynthetic Process Dehydrodolichyl Diphosphate Synthase Complex Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity Euchromatin Antibacterial Humoral Response Myosin II Heavy Chain Binding Histone H2AXY142 Phosphatase Activity Chromatin DNA Binding	Descending Aorta Development Lung Development Ascending Aorta Development Peptidyl-lysine Oxidation Protein-lysine 6-oxidase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Protein Oxidation Postsynaptic Endosome Negative Regulation Of Clathrin-dependent Endocytosis Synaptic Target Recognition Phosphoserine Residue Binding Golgi Reassembly Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Establishment Of Golgi Localization Regulation Of Bone Development Elastic Fiber Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?