C14orf180 and AQP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C14orf180	AQP3
Description		chromosome 14 open reading frame 180	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity Identical Protein Binding
	Biological Process		Positive Regulation Of Immune System Process Response To Ischemia Renal Water Homeostasis Water Transport Glycerol Transmembrane Transport Urea Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Establishment Of Localization In Cell Transmembrane Transport Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs			Bisacodyl Sennosides
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Rheumatoid arthritis ( 30891314)	Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		47 interacting genes: AQP3 AQP6 ARL13B ASZ1 BIK CD74 CD79A CISD2 CLEC7A CPLX4 CYBC1 EBAG9 ERGIC3 FAM174A FAM209A GPR152 GPRC5D GPX8 HAS3 KASH5 KCNJ6 LHFPL5 LIME1 MFF MGST3 MUC1 NCR3LG1 PDZK1IP1 PPP1CB PPP1CC REEP4 SAR1A SLC10A6 SLC35H1 SLC71A2 TEX29 TIMMDC1 TM4SF19 TMEM106C TMEM14B TMEM167B TMEM207 TMEM31 TMEM51 TMEM80 VSIR ZDHHC15	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		400258	360
HPRD ID		17383	08970
Ensembl ID		ENSG00000184601	ENSG00000165272
Uniprot IDs		B4DN93 J3KNP8 Q8N912	A0A2R8Y2R4 B4E034 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding B Cell Receptor Complex PTW/PP1 Phosphatase Complex	Membrane
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